RO 31-8220 METHANESULFONATE Chemische Eigenschaften,Einsatz,Produktion Methoden
Biologische Aktivit?t
Protein kinase C inhibitor, with activity at other protein kinases (IC 50 values are 33, 3, 8, 15 and 38 nM for PKC α , MAPKAP-K1b, MSK1, GSK3 β and S6K1 respectively). Activates JNK and glycogen synthase, and inhibits MAPK and ERK2, in rat adipocytes and L6 myotubes. Also inhibits voltage-dependent Na + channels in the micromolar range.
RO 31-8220 METHANESULFONATE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte