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RO 31-8220 METHANESULFONATE

RO 31-8220 METHANESULFONATE Struktur
125314-64-9
CAS-Nr.
125314-64-9
Englisch Name:
RO 31-8220 METHANESULFONATE
Synonyma:
RO-31-8220;RO 31-8220 MESYLATE;BisindolylMaleiMide IX;Bisindoylmaleimidine IX;RO 31-8220 METHANESULFONATE;Ro 31-8220 methanesulfonate salt;BISINDOLYLMALEIMIDE IX METHANESULFONATE;BISINDOYLMALEIMIDINE IX METHANESULFONATE;Ro 31-8220 mesylate (Bisindolylmaleimide IX);3-[1-3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL) MALEIMIDE
CBNumber:
CB4355393
Summenformel:
C25H23N5O2S
Molgewicht:
457.55
MOL-Datei:
125314-64-9.mol

RO 31-8220 METHANESULFONATE Eigenschaften

Dichte
1.42±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
H2O: 7.3 mg/mL
pka
7.90±0.60(Predicted)
Aggregatzustand
solid
Farbe
orange to red

Sicherheit

WGK Germany  3

RO 31-8220 METHANESULFONATE Chemische Eigenschaften,Einsatz,Produktion Methoden

Biologische Aktivit?t

Protein kinase C inhibitor, with activity at other protein kinases (IC 50 values are 33, 3, 8, 15 and 38 nM for PKC α , MAPKAP-K1b, MSK1, GSK3 β and S6K1 respectively). Activates JNK and glycogen synthase, and inhibits MAPK and ERK2, in rat adipocytes and L6 myotubes. Also inhibits voltage-dependent Na + channels in the micromolar range.

RO 31-8220 METHANESULFONATE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


RO 31-8220 METHANESULFONATE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 76)Lieferanten
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Shanghai Boyle Chemical Co., Ltd.
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125314-64-9()Verwandte Suche:


  • BISINDOLYLMALEIMIDE IX METHANESULFONATE
  • BISINDOYLMALEIMIDINE IX METHANESULFONATE
  • RO-31-8220
  • RO 31-8220 MESYLATE
  • RO 31-8220 METHANESULFONATE
  • 3-[3-[2,5-DIHYDRO-4-(1-METHYL-1H-INDOL-3-YL)-2,5-DIOXO-1H-PYRROL-3-YL]-1H-INDOL-1-YL]PROPYL CARBAMIMIDOTHIOIC ACID ESTER MESYLATE
  • 3-[1-3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL) MALEIMIDE
  • 3-[1-[3-(AMIDINOTHIO)PROPYL-1H-INDOL-3-YL]-3-(1-METHYL-1H-INDOL-3-YL)MALEIMIDE METHANESULFONATE
  • 2-[1-[3-(AMIDINOTHIO)PROPYL]-1H-INDOL-3-YL]-3-(1-METHYLINDOL-3-YL)-MALEIMIDE METHANESULFONATE
  • BisindolylMaleiMide IX
  • 2-{1-[3-(Amidinothio)propyl]-1H-indol-3-yl}-3-(1-methylindol-3-yl)maleimide methanesulfonate salt
  • Bisindoylmaleimidine IX
  • Ro 31-8220 methanesulfonate salt
  • 3-[1-[3-(Amidinothio)propyl-1H-indol-3-yl]-3-(1-methyl-1H-indol-3-yl)maleimide] meslate
  • Ro 31-8220 mesylate (Bisindolylmaleimide IX)
  • Carbamimidothioic acid, 3-(3-(2,5-dihydro-4-(1-methyl-1H-indol-3-yl)-2,5-dioxo-1H-pyrrol-3-yl)-1H-indol-1-yl)propyl ester
  • 125314-64-9
  • C25H23N5O2SCH3SO3H
  • Protein Kinase
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