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N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat

SUFENTANIL CITRATE Struktur
60561-17-3
CAS-Nr.
60561-17-3
Bezeichnung:
N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat
Englisch Name:
SUFENTANIL CITRATE
Synonyma:
r33800;Sufenta;Sufentanil Forte;r30730citratesalt;sufentanylcitrate;Sufentanyl Citrat;SUFENTANIL CITRATE;SUFENTANILCITRATE,USP;Sufentanil citrate salt;Rezvilutamide Impurity 38
CBNumber:
CB4339496
Summenformel:
C28H38N2O9S
Molgewicht:
578.68
MOL-Datei:
60561-17-3.mol

N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat Eigenschaften

Schmelzpunkt:
96.60C
Flammpunkt:
9℃
storage temp. 
-20°C Freezer
L?slichkeit
H2O: soluble1mg/mL, clear
Aggregatzustand
powder
Farbe
white to beige
Stabilit?t:
Hygroscopic

Sicherheit

Kennzeichnung gef?hrlicher T+,T,F
R-S?tze: 26/27/28-39/23/24/25-23/24/25-11
S-S?tze: 26-27-28-36/37/39-45-36/37-16-7
RIDADR  3249
WGK Germany  3
HazardClass  6.1(b)
PackingGroup  III
HS Code  2934910000
Toxizit?t LD50 intravenous in dog: 14100ug/kg

N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

Crystalline Solid

Verwenden

Potent derivative of Fentanyl. Analgesic (narcotic). Controlled substance (opiate)

Allgemeine Beschreibung

Sufentanil is a short acting synthetic opioid analgesic most commonly used for pain relief during medical operations. This certified solution standard is applicable to use in clinical toxicology, pain prescription monitoring, or forensic analysis by LC-MS/MS or GC/MS. Sufentanil is sold under the trade name Sufenta.

Clinical Use

Addition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity. The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its greater sedative and analgesic potency, sufentanil produces less respiratory depression at effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short duration is caused by redistribution from brain tissues after intravenous dosage.

N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

60561-17-3(N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat)Verwandte Suche:


  • SUFENTANIL CITRATE
  • n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-n-phenylpropionam
  • n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)-propionanilidcitr
  • n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilidecitrat
  • r30730citratesalt
  • r33800
  • sufentanylcitrate
  • N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamide citrate
  • SUFENTANILCITRATE,USP
  • Propanamide, N-[4-(methoxymethyl)-1-[2- (2-thienyl)ethyl]-4-piperidinyl]-N-phenyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
  • N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenyl, propanamide 2-Hydroxy-1,2,3-propanetricarboxylate
  • Sufenta
  • Sufentanil Forte
  • Sufentanyl Citrat
  • Sufentanil Citrate CII (25 mg)
  • Methanol(Test:Sufentanil Citrate, 100 μg/mL as free base)
  • Sufentanil Citrate (CII), USP
  • Sufentanil Citrate solution
  • N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenylpropanamide citrate
  • Sufentanil Citrate CII (1623648)
  • Sufentanil citrate salt
  • OJCZPLDERGDQRJ-UHFFFAOYSA-N
  • Rezvilutamide Impurity 38
  • 60561-17-3
  • C22H30N2O2SC6H8O7
  • C28H38N2O9S
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Organics
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