N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat
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- CAS-Nr.
- 60561-17-3
- Bezeichnung:
- N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat
- Englisch Name:
- SUFENTANIL CITRATE
- Synonyma:
- r33800;Sufenta;Sufentanil Forte;r30730citratesalt;sufentanylcitrate;Sufentanyl Citrat;SUFENTANIL CITRATE;SUFENTANILCITRATE,USP;Sufentanil citrate salt;Rezvilutamide Impurity 38
- CBNumber:
- CB4339496
- Summenformel:
- C28H38N2O9S
- Molgewicht:
- 578.68
- MOL-Datei:
- 60561-17-3.mol
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N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat Eigenschaften
- Schmelzpunkt:
- 96.60C
- Flammpunkt:
- 9℃
- storage temp.
- -20°C Freezer
- L?slichkeit
- H2O: soluble1mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- white to beige
- Stabilit?t:
- Hygroscopic
Sicherheit
N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat Chemische Eigenschaften,Einsatz,Produktion Methoden
Chemische Eigenschaften
Crystalline Solid
Verwenden
Potent derivative of Fentanyl. Analgesic (narcotic).
Controlled substance (opiate)
Allgemeine Beschreibung
Sufentanil is a short acting synthetic opioid analgesic most commonly used for pain relief during medical operations. This certified solution standard is applicable to use in clinical toxicology, pain prescription monitoring, or forensic analysis by LC-MS/MS or GC/MS. Sufentanil is sold under the trade name Sufenta.
Clinical Use
Addition of the 4-methoxymethyl group and bioisosteric replacement of the phenyl with a 2-thiophenyl on the fentanyl structure results in a 10-fold increase in μ opioid activity.
The resultant compound, sufentanil, is 600 to 800 times more potent than morphine. Despite its
greater sedative and analgesic potency, sufentanil produces less respiratory depression at
effective anesthetic doses. Sufentanil is available in an intravenous dosage form, and it is used for
anesthetic procedures. It has a faster onset and shorter duration of action than fentanyl. The short
duration is caused by redistribution from brain tissues after intravenous dosage.
N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
60561-17-3(N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamidcitrat)Verwandte Suche:
- SUFENTANIL CITRATE
- n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidinyl)-n-phenylpropionam
- n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)-propionanilidcitr
- n-(4-(methoxymethyl)-1-(2-(2-thienyl)ethyl)-4-piperidyl)propionanilidecitrat
- r30730citratesalt
- r33800
- sufentanylcitrate
- N-[4-(methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl]-N-phenylpropionamide citrate
- SUFENTANILCITRATE,USP
- Propanamide, N-[4-(methoxymethyl)-1-[2- (2-thienyl)ethyl]-4-piperidinyl]-N-phenyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
- N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenyl, propanamide 2-Hydroxy-1,2,3-propanetricarboxylate
- Sufenta
- Sufentanil Forte
- Sufentanyl Citrat
- Sufentanil Citrate CII (25 mg)
- Methanol(Test:Sufentanil Citrate, 100 μg/mL as free base)
- Sufentanil Citrate (CII), USP
- Sufentanil Citrate solution
- N-[4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidinyl]-N-phenylpropanamide citrate
- Sufentanil Citrate CII (1623648)
- Sufentanil citrate salt
- OJCZPLDERGDQRJ-UHFFFAOYSA-N
- Rezvilutamide Impurity 38
- 60561-17-3
- C22H30N2O2SC6H8O7
- C28H38N2O9S
- Aromatics
- Heterocycles
- Intermediates & Fine Chemicals
- Pharmaceuticals
- Organics