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2'-Deoxy-L-thymidine

2'-Deoxy-L-thymidine Struktur
3424-98-4
CAS-Nr.
3424-98-4
Englisch Name:
2'-Deoxy-L-thymidine
Synonyma:
Ldt;L-Dt;Sebivo;NV 02B;Epavudine;Aids112549;elbivudine;Aids-112549;L-Deoxythymidine;BETA-L-THYMIDINE
CBNumber:
CB4321891
Summenformel:
C10H14N2O5
Molgewicht:
242.23
MOL-Datei:
3424-98-4.mol

2'-Deoxy-L-thymidine Eigenschaften

Schmelzpunkt:
188-190°C
alpha 
D20 -20.3° (c = 0.192 in water)
Dichte
1.452±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
L?slichkeit
H2O: soluble10mg/mL (clear solution)
pka
9.55±0.10(Predicted)
Aggregatzustand
powder
Farbe
white to beige
Optische Aktivit?t
[α]/D -15 to -22°, c = 1 in H2O
InChIKey
IQFYYKKMVGJFEH-CSMHCCOUSA-N
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 22
S-S?tze: 24/25
WGK Germany  3
RTECS-Nr. UV9048500
HS Code  29349990
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit
P280 Schutzhandschuhe/Schutzkleidung/Augenschutz tragen.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

2'-Deoxy-L-thymidine Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Telbivudine is a b-L-thymidine nucleoside analog launched for the once-daily oral treatment of chronic hepatitis B virus (HBV) infection. It is the fourth nucleoside or nucleotide analog to be marketed for this indication. The previous drugs from this class include lamivudine, a deoxythiacytosine analog, adefovir, a nucleotide analog, and entecavir, a guanosine analog. Adefovir, entecavir, and telbivudine are specifically indicated for HBV, whereas lamivudine is indicated for both HBV and HIV infections. Telbivudine is efficiently phosphorylated by cellular kinases to the active triphosphate derivative, which inhibits HBV DNA polymerase by competing with the natural substrate, thymidine- 5’-triphosphate.

Chemische Eigenschaften

2'-Deoxy-L-thymidine is White Solid

Definition

ChEBI: A pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase.

2'-Deoxy-L-thymidine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2'-Deoxy-L-thymidine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 315)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12834 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886
info@dakenam.com China 18751 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32957 60
career henan chemical co
+86-0371-86658258 +8613203830695
sales@coreychem.com China 29880 58
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293
sales@sdzschem.com China 2930 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830
figo.gao@foxmail.com China 8497 58
Beijing Ribio Biotech Co.,Ltd
010-62664360 +8613328773880
wucy@ribio.com.cn China 117 58
Yunbio Tech Co.,Ltd.
+86-010-60605551 +86-18046518538
yunbiochem@126.com China 321 58

3424-98-4()Verwandte Suche:


  • 2'-Deoxy-L-thyMidine(Telbivudine)
  • Telbivudine(Tyzeka, Sebivo)
  • 1-(2-Deoxy-β-L-erythro-pentofuranosyl)-5-Methyl-
  • Telbivudine(L-ThyMidine,LDT-600)
  • 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxyMethyl)oxolan-2-yl]-5-Methyl-1,2,3,4-tetrahydropyriMidine-2,4-dione
  • 2,4(1H,3H)-PyriMidinedione,1-(2-deoxy-b-L-erythro-pentofuranosyl)-5-Methyl-
  • Sebivo
  • Telbivudine(L-ThyMidine)
  • Telbivudine, >=98%
  • 1-(2-Deoxy--L-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
  • 1-(2-deoxy--L-erythro-pentofuranosyl)thymine
  • Epavudine
  • NV 02B
  • Aids112549
  • Aids-112549
  • L-Deoxythymidine
  • Ldt
  • L-Dt
  • Thymine, 1-(2-deoxy-.beta.-L-erythro-pentofuranosyl)-
  • BETA-L-THYMIDINE
  • 2'-DEOXY-L-THYMIDINE
  • L-Thymidine(Telbivudine)
  • 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-pyrimidine-2,4-dione
  • Β-L-2'-DEOXY-THYMIDINE
  • 1-[(2S,4R,5S)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
  • 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-L-erythro-pentofuranosyl)-5-methyl-
  • elbivudine
  • 2'-Deoxy-L-thymidine USP/EP/BP
  • Telbivudine (Epavudine)
  • Telbivudine 13C 15N2
  • Inhibitor,Telbivudine,inhibit,HBV,Hepatitis B virus
  • 1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
  • 2'-Deoxy-L-thymidine
  • 3424-98-4
  • Anti-virals
  • Bases & Related Reagents
  • Carbohydrates & Derivatives
  • Intermediates & Fine Chemicals
  • Nucleotides
  • Pharmaceuticals
  • API intermediates
  • Amines
  • API
  • Chiral Reagents
  • Heterocycles
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