Anti-Retinoic acid-induced protein 3 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
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Biochem/physiol Actions
GPRC5A (G protein-coupled receptor, class C, group 5, member A) gene encodes a protein belonging to the type 3 G protein-coupling receptor family, which contain signature 7-transmembrane domain motif. The encoded protein is also called as retinoic acid-induced gene 1 (RAIG1). The type 3 GPRC family also contains metabotropic glutamate receptors, GABAB receptors, calcium-sensing receptors and pheromone receptors. GPRC5A is mainly expressed in the brain and its expression is regulated by retinoic acid. It may act as a tumor suppressor in lung tissue. However, some studies have shown that GPRC5A expression promotes breast cancer cell proliferation. It may bind to Frizzled proteins and may activate non-canonical Wnt signaling.
Anti-Retinoic acid-induced protein 3 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
