4-Hydroxyalternariol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

4-hydroxy Alternariol is a metabolite of the mycotoxin alternariol formed through cytochrome P450 (CYP450) metabolism. It increases reactive oxygen species (ROS) in KYSE510 human esophageal cells by 701% compared to control. 4-hydroxy Alternariol increases topoisomerase IIβ-DNA complexes by 208% compared to control in an ICE assay but does not induce DNA damage in KYSE510 cells. It completely inhibits topoisomerase IIα activity at a concentration of 25 μM under cell-free conditions.

Verwenden

4-Hydroxyalternariol is the fully demethylated tetraphenol analogue of the benzopyranone graphislactones. Hydroxyalternariol was isolated as a major co-metabolite of a graphislactone A-producing fungus. Hydroxyalternariol has not previously been available for study and no bioactivity has been reported to date.

4-Hydroxyalternariol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

4-Hydroxyalternariol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
BOC Sciences	16314854226; +16314854226	inquiry@bocsci.com	United States	19741	58
Chengdu RunZeBenTu Chemical Co., Ltd	13096311329 028-88469284 616445927	616445927@qq.com	China	2874	50
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Lynnchem	86-(0)29-85992781 17792393971	info@lynnchem.com	China	4587	58
Novachemistry	44-20819178-90 02081917890	info@novachemistry.com	United Kingdom	4381	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57423	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Meng Cheng Technology (Shanghai) Co., LTD	400-820-6829	sales@mitachieve.com	China	8860	58
Shanghai Saikerui Biotechnology Co. , Ltd.	021-58000709 15900491054	info@scrbio.com	China	10329	58
Nanjing Shizhou Biology Technology Co.,Ltd	025-85560043 15850508050	cindy.huang@synzest.com	China	12000	58

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• 4-Hydroxyalternariol
• Hydroxyalternariol, 4-
• 3,4,7,9-tetrahydroxy-1-methylbenzo[c]chromen-6-one
• 6H-Dibenzo[b,d]pyran-6-one, 3,4,7,9-tetrahydroxy-1-methyl-
• Alternariol Impurity 18
• 3,4,7,9-tetrahydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one
• 959417-21-1