N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Ceramides linked to 2-hydroxy fatty acids (hFA) are present in the surface epithelium of the skin. 20:0(2S-OH) Ceramide is a unique ceramide containing 20C long chain base fatty acid (arachidic acid)-with 2′-hydroxyl group in S configuration.

Biochem/physiol Actions

Hydroxy fatty acid (hFA)-sphingolipids help in formation and function of myelin. In addition, they also play a vital role in cell signaling, cell differentiation and apoptosis. In epidermis, hFA-ceramides aid in permeability barrier function. NAD(P)H-dependent enzyme, fatty acid 2-hydroxylase (FA2H) catalyzes the synthesis of hFA-ceramides. FA2H gene mutation leads to the development of neurological disorders such as leukodystrophy and spastic paraparesis in humans. hFA-ceramides help PM02734 (elisidepsin), an?antitumor drug to exhibit its activity.

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Creative Enzymes	1-516-855-7709	info@creative-enzymes.com	United States	8748	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Codow Chemical Co.,Ltd.	18620099427	amy@howeipharm.com	China	17687	55
Chengdu Dianchun Technology Co., Ltd	400-1166-196 18502815961	cdhxsj@163.com	China	14603	60
SHANGHAI ZZBIO CO., LTD.	15102117276 19921389125	tech@zzbioco.com	China	12065	58

---

• N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
• 20:0(2S-OH) Ceramide
• N-(2'-(S)-HYDROXYARACHIDOYL)-D-ERYTHRO-SPHINGOSINE;20:0(2S-OH) CERAMIDE
• Eicosanamide, 2-hydroxy-N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-, (2S)-
• N-(2'-(S)-hydroxyarachidoyl)-D-erythro-sphingosine
• 1246298-48-5