(1R,2S)-2-fluorocyclopropanecarboxylic acid
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- CAS-Nr.
- 167073-08-7
- Englisch Name:
- (1R,2S)-2-fluorocyclopropanecarboxylic acid
- Synonyma:
- (1R,2S)-2-fluorocyclopropane-1-carboxylic acid;Sitafloxacin Impurity 26;(1R,2S)-2-fluorocyclopropanecarboxylic acid;(1R,2S)-trans-2-Fluorocyclopropanecarboxylic acid 97%;Cyclopropanecarboxylic acid, 2-fluoro-, (1R-trans)- (9CI)
- CBNumber:
- CB42610540
- Summenformel:
- C4H5FO2
- Molgewicht:
- 104.08
- MOL-Datei:
- 167073-08-7.mol
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(1R,2S)-2-fluorocyclopropanecarboxylic acid Eigenschaften
- Siedepunkt:
- 202.3±33.0 °C(Predicted)
- Dichte
- 1.35±0.1 g/cm3(Predicted)
- pka
- 4.00±0.11(Predicted)
- InChI
- InChI=1S/C4H5FO2/c5-3-1-2(3)4(6)7/h2-3H,1H2,(H,6,7)/t2-,3-/m0/s1
- InChIKey
- HZQKMZGKYVDMCT-HRFVKAFMSA-N
- SMILES
- [C@H]1(C(O)=O)C[C@@H]1F
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H225 |
Flüssigkeit und Dampf leicht entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 2 |
Achtung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
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| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P243 |
Ma?nahmen gegen elektrostatische Entladungen treffen. |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P403 |
An einem gut belüfteten Ort aufbewahren. |
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(1R,2S)-2-fluorocyclopropanecarboxylic acid Chemische Eigenschaften,Einsatz,Produktion Methoden
Synthese
Dissolve benzyl alcohol and allyl bromide in the solvent, add sodium hydride, and perform a condensation reaction to obtain allyl benzyl ether. The obtained allyl benzyl ether, dichlorofluoromethane, and sodium hydroxide solution are raw materials for carbene reaction to obtain 2-chloro-2-fluorocyclopropylmethyl benzyl ether. Subsequently, the obtained 2-chloro-2-fluorocyclopropylmethylbenzyl ether is hydrogenated and reduced to obtain 2-chloro-2-fluorocyclopropanemethanol. Sodium hypochlorite is added as an oxidizing agent to perform an oxidation reaction to obtain 2-chloro-2-fluorocyclopropanecarboxylic acid. Finally, diethylamine is added to perform a hydrogenation reduction reaction to obtain (1R,2S)-2-fluorocyclopropanecarboxylic acid.
(1R,2S)-2-fluorocyclopropanecarboxylic acid Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(1R,2S)-2-fluorocyclopropanecarboxylic acid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 60)Lieferanten
167073-08-7()Verwandte Suche:
- (1R,2S)-2-fluorocyclopropanecarboxylic acid
- Cyclopropanecarboxylic acid, 2-fluoro-, (1R-trans)- (9CI)
- (1R,2S)-trans-2-Fluorocyclopropanecarboxylic acid 97%
- Sitafloxacin Impurity 26
- (1R,2S)-2-fluorocyclopropane-1-carboxylic acid
- 167073-08-7
