HPI-1 Hydrate Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

HPI-1 (hydrate) is a Hedgehog (Hh) pathway inhibitor that suppresses signaling through Sonic Hh (IC₅₀ = 1.5 μM) without significantly affecting Wnt signaling (IC₅₀ ≥ 30 μM). HPI-1 suppresses Hh activation induced by loss of Suppressor of Fused or by Gli overexpression, suggesting action at posttranslational modification of Gli protein or at the interaction of Gli with a co-factor. HPI-1 (hydrate) also inhibits signaling through the oncogenic Smoothened (Smo) mutant SmoM2 in neuron precursors, preventing cell proliferation.

Verwenden

HPI-1 is a Hedgehog pathway inhibitor; Gli1/Gli2 inhibitor.

HPI-1 Hydrate Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

HPI-1 Hydrate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
J & K SCIENTIFIC LTD.	010-82848833 400-666-7788	jkinfo@jkchemical.com	China	96815	76
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15402	60
Shanghai TaoSu Biochemical Technology Co., Ltd.	021-33632979	info@tsbiochem.com	China	8065	58
Shenzhen Polymeri Biochemical Technology Co., Ltd.	+86-400-002-6226 +86-13028896684;	sales@rrkchem.com	China	57423	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44807	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58

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