aprinocarsen Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Treatment of non-small
cell lung cancer (antisense oligonucleotide; protein kinase
C-alpha inhibitor).
Trademarks
Affinitak (Isis).
Clinical Use
Aprinocarsen is a phosphorothioate antisense agent targeted against protein kinase Cα,
a protein that is implicated in malignant transformation and proliferation. It showed
activity in Phase I and Phase II clinical trials against nonsmall-cell lung cancer when
used in combination with cisplatin or the combination of cisplatin and gemcitabine.
aprinocarsen Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte