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(S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-desoxy-N,N-dimethyladenosindihydrochlorid

PUROMYCIN DIHYDROCHLORIDE Struktur
58-58-2
CAS-Nr.
58-58-2
Bezeichnung:
(S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-desoxy-N,N-dimethyladenosindihydrochlorid
Englisch Name:
PUROMYCIN DIHYDROCHLORIDE
Synonyma:
pdh;PUROMYCIN;PUROMYCIN 2HCL;l-2hc;abs9143;Purinomycin;-9H-purin-9-yl);Puromycin dihydrochL;P638 dihydrochloride;-5-(6-(dimethylamino)
CBNumber:
CB4152905
Summenformel:
C22H30ClN7O5
Molgewicht:
507.98
MOL-Datei:
58-58-2.mol

(S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-desoxy-N,N-dimethyladenosindihydrochlorid Eigenschaften

Schmelzpunkt:
168-170℃
storage temp. 
Inert atmosphere,Store in freezer, under -20°C
L?slichkeit
H2O: soluble50mg/mL (Sterilize stock solution by filtration using 0.22 μm filter then store in aliquots at 20 °C.)
Aggregatzustand
solution
Farbe
yellow-white
Wasserl?slichkeit
Soluble in water
Merck 
14,7943
BRN 
3853613
Stabilit?t:
Stable. Heat sensitive. Incompatible with strong oxidizing agents.
InChIKey
MKSVFGKWZLUTTO-NGOAXYITSA-N
EPA chemische Informationen
Adenosine, 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-, dihydrochloride (58-58-2)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xn
R-S?tze: 22-40
S-S?tze: 24/25
RIDADR  3249
WGK Germany  3
RTECS-Nr. AU7355000
F  3-8-10
HazardClass  6.1(b)
PackingGroup  III
HS Code  29419090
Toxizit?t LD50 oral in guinea pig: 600mg/kg
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H302 Gesundheitssch?dlich bei Verschlucken. Akute Toxizit?t oral Kategorie 4 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P270, P301+P312, P330, P501
Sicherheit

(S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-desoxy-N,N-dimethyladenosindihydrochlorid Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R22:Gesundheitssch?dlich beim Verschlucken.
R40:Verdacht auf krebserzeugende Wirkung.

Chemische Eigenschaften

white powder

Verwenden

Puromycin dihydrochloride is the salt of puromycin, a nucleoside antibiotic isolated from Streptomyces alboniger in the 1950s as an anti-trypansomal agent with antibiotic activity. While the salt shares the same pharmacological properties as puromycin free base, its greater water solubility offers advantages in some in vitro applications. Physicochemical properties and chromatographic behaviour will depend on whether the pH is buffered. In non-pH controlled systems, the free base and salt may behave differently.

Allgemeine Beschreibung

White powder.

Air & Water Reaktionen

Water soluble.

Reaktivit?t anzeigen

PUROMYCIN DIHYDROCHLORIDE is sensitive to prolonged exposure to heat. . Behaves as a very weak acid in solution.

Brandgefahr

Flash point data for PUROMYCIN DIHYDROCHLORIDE are not available, but PUROMYCIN DIHYDROCHLORIDE is probably combustible.

l?uterung methode

Puromycin dihydrochloride is purified by recrystallisation from H2O. The free base, [58-60-6] M 294.3, has m 175.5-177o (172-173o) (from H2O). The sulfate has m 180-187o dec (from H2O), and the picrate monohydrate has m 146-149o (from H2O). [Baker et al. J Am Chem Soc 77 1 1955, Fryth et al. J Am Chem Soc 80 3736 1958.] It is an inhibitor of aminopeptidase and terminates protein synthesis [Reboud et al. Biochemistry 20 5281 1981]. [Beilstein 26 III/IV 3704.]

(S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-desoxy-N,N-dimethyladenosindihydrochlorid Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-desoxy-N,N-dimethyladenosindihydrochlorid Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 294)Lieferanten
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58-58-2((S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-desoxy-N,N-dimethyladenosindihydrochlorid)Verwandte Suche:

  • Puromycin dihydrochloride hydrate,99%
  • 3’-(alpha-amino-p-methoxyhydrocinnamamido)-3’-deoxy-n,n-dimethyl-adenosin
  • adenosine,3’-((2-amino-3-(4-methoxyphenyl)-1-oxopropyl)amino)-3’-deoxy-n,n-dim
  • dihydrochloride,(s)-ethyl
  • PUROMYCIN Dihydrochloride Dihydrate 96%
  • 3'-[[12-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYL-ADENOSINE 2HCL
  • 3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
  • 3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYL-ADENOSINE 2HCL
  • 3'-(A-AMINO-P-METHOXYHYDROCINNAMAMIDO)-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
  • 3'-(A-AMINO-P-METHOXY-HYDOCINNAMAMIDO)-3'-DEXOY-N,N-DIMETHYLADENOSINE 2HCL
  • 3'-(ALPHA-AMINO-P-METHOXY-HYDROCINNAMINO-3'-DEOXY-N,N-DIMETHY-ADENOSINE) 2HCL
  • 3'-(ALPHA-AMINO-P-METHOXY-HYDROCINNAMIDO-3'-DEOXY-N,N-DIMETHYL-ADENOSINE) 2HCL
  • 3'-[ALPHA-AMINO-P-METHOXYHYDROCINNAMAMIDO]-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
  • 3'-(ALPHA-AMINO-P-METHOXYHYDROCINNAMAMIDO)-3'-DEOXY-N,N-DIMETHYLADENOSINE, 2HCL
  • 3'-(ALPHA-AMINO-P-METHOXYHYDROCINNAMADIO)-3'-DEOXY-N,N-DIMETHYLADENOSINE DIHYDROCHLORIDE
  • PUROMYCIN, CELL CULTURE TESTED
  • Puromycin, 3-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3-deoxy-N,N-dimethyladenosine dihydrochloride
  • Puromycin hydrate dihydrochloride
  • PuroMycin dihydrochloride hydrate, 99% 10MG
  • PuroMycin dihydrochlorid
  • Puromycin dihydrochloride (animal free)
  • StyloMycin dihydrochloride, CL 13900 dihydrochloride, CL16536, NSC 3055, P638 dihydrochloride.
  • 3'-[[(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine,hydrochloride (1:2)
  • Puromycin 2HCl (S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
  • Puromycin dihydrochloride (S)-3'-[[2-Amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
  • Puromycin 2hydrochloride
  • -2-Amino-N-((2S,3S,4R,5R)
  • -4-hydroxy-2-(hydroxymethyl)
  • -5-(6-(dimethylamino)
  • -9H-purin-9-yl)
  • propanamide dihydrochloride
  • tetrahydrofuran-3-yl)
  • PUROMYCIN DIHYDROCHLORIDE
  • (S) 3'-[[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYLADENOSINE 2HCL
  • (S)-3'-[2-AMINO-3-(4-METHOXYPHENYL)-1-OXOPROPYL]AMINO]-3'-DEOXY-N,N-DIMETHYLADENOSINE
  • l-2hc
  • puromycinhydrochloride
  • stylomycinhydrochloride
  • PUROMYCIN DIHYDROCHLORIDE CELL*CULTURE T ESTED
  • PUROMYCIN READY MADE SOLUTION
  • PUROMYCIN DIHYDROCHLORIDE FROM STREPTO-M YCES ALBO-NIGER
  • (S)-3'-[[2-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine dihydrochloride
  • PUROMYCIN DIHYDROCHLORIDE CELL CULTURE REAGENT
  • PUROMYCIN DIHYDROCHLORIDE ULTRA PURE GRADE 98+%
  • Puromycin.Cellculturedtested
  • Puromycin,Solution,CellCultureTested
  • Adenosine, 3-(2S)-2-amino-3-(4-methoxyphenyl)-1-oxopropylamino-3-deoxy-N,N-dimethyl-, dihydrochloride
  • 3'-[α-amino-p-methoxyhydrocinnamamido]-3'-deoxy-n,n-dimethyladenosine dihydrochloride
  • PUROMYCINDIHYROCHLORIDE
  • DIHYDROGEN PUROMYCIN DICHLORIDE
  • Puromycin dihydrochL
  • CL 13900 dihydrochloride
  • P638 dihydrochloride
  • STYLOMYCIN HYDROCHLORIDE; CL 13900 DIHYDROCHLORIDE; CL16536; NSC 3055; P638 DIHYDROCHLORIDE
  • PUROMYCIN DIHYDROCHLORIDE USP/EP/BP
  • abs9143
  • (S)-2-Amino-N-((2S,3S,4R,5R)-5-(6-(Dimethylamino)-9H-purin-9-yl)-4-hydroxy-2-(hydroxymethyl)tetrahydrofuran-3-yl)-3-(4-methoxyphenyl)propanamide dihydrochloride
  • Puromycin 2HCl (CL13900)
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