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Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Struktur
1904651-39-3
CAS-Nr.
1904651-39-3
Englisch Name:
Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-
Synonyma:
7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline;7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinoline;7-(dif luoromethyl)-6-(1 -methyl-1 H-pyrazol-4-y1)-1,2,3,4-tetrahydroquinoline;Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-
CBNumber:
CB38085848
Summenformel:
C14H15F2N3
Molgewicht:
263.29
MOL-Datei:
1904651-39-3.mol

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Eigenschaften

Siedepunkt:
440.6±45.0 °C(Predicted)
Dichte
1.33±0.1 g/cm3(Predicted)
L?slichkeit
Dichloromethane; Ethyl Acetate; Methanol
pka
3.96±0.20(Predicted)
Aggregatzustand
Solid
Farbe
Off-White

Sicherheit

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline is an intermediate in the synthesis of GNE-781 (D447825), a derivative of a highly advanced, potent and selective bromodomain inhibitor of cyclic adenosine monophosphate response element binding protein (CBP). Inhibition of the bromodomain of the transcriptional regulator CBP/P300 is an especially interesting new therapeutic approach in oncology.

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)- Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 13)Lieferanten
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  • Quinoline, 7-(difluoromethyl)-1,2,3,4-tetrahydro-6-(1-methyl-1H-pyrazol-4-yl)-
  • 7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinoline
  • 7-(Difluoromethyl)-6-(1-methylpyrazol-4-yl)-1,2,3,4-tetrahydroquinoline
  • 7-(dif luoromethyl)-6-(1 -methyl-1 H-pyrazol-4-y1)-1,2,3,4-tetrahydroquinoline
  • 1904651-39-3
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