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2,3-Didehydro-D-erythro-hexono-1,4-lacton

Erythorbic Acid Struktur
89-65-6
CAS-Nr.
89-65-6
Bezeichnung:
2,3-Didehydro-D-erythro-hexono-1,4-lacton
Englisch Name:
Erythorbic Acid
Synonyma:
D-ISOASCORBIC ACID;(5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one;ISOASCORBIC ACID;ERYTHORBATE;araboascorbicacid;D-ARABOASCORBIC ACID;d-arabino-ascorbicacid;Ascorbic Acid EP Impurity F;2,3-didehydro-d-erythro-hexono-1,4-lactone;mercate5
CBNumber:
CB3777943
Summenformel:
C6H8O6
Molgewicht:
176.12
MOL-Datei:
89-65-6.mol

2,3-Didehydro-D-erythro-hexono-1,4-lacton Eigenschaften

Schmelzpunkt:
169-172 °C (dec.) (lit.)
alpha 
-17.25 º (c=10, H2O 25 ºC)
Siedepunkt:
227.71°C (rough estimate)
Dichte
1.3744 (rough estimate)
Dampfdruck
0Pa at 25℃
FEMA 
2410 | ERYTHROBIC ACID
Brechungsindex
-17.5 ° (C=10, H2O)
storage temp. 
2-8°C
L?slichkeit
H2O: 0.1 g/mL, clear, colorless to very faintly yellow
Aggregatzustand
Crystals or Crystalline Powder
pka
4.09±0.10(Predicted)
Farbe
White to slightly yellow
Geruch (Odor)
odorless
Optische Aktivit?t
[α]25/D 16.8°, c = 2 in H2O
Wasserl?slichkeit
1g/10mL
Merck 
14,5126
BRN 
84271
Stabilit?t:
Stable. Combustible. Incompatible with chemically active metals, aluminium, zinc, copper, magnesium, strong bases, strong oxidizing agents.
InChIKey
CIWBSHSKHKDKBQ-JLAZNSOCSA-N
LogP
-1.69 at 25℃
CAS Datenbank
89-65-6(CAS DataBase Reference)
EPA chemische Informationen
Isoascorbic acid (89-65-6)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/37/38
S-S?tze: 26-24/25
WGK Germany  2
RTECS-Nr. KF3015000
TSCA  Yes
HS Code  29329990
Giftige Stoffe Daten 89-65-6(Hazardous Substances Data)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H315 Verursacht Hautreizungen. Hautreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P302+P352, P321,P332+P313, P362
H319 Verursacht schwere Augenreizung. Schwere Augenreizung Kategorie 2 Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" /> P264, P280, P305+P351+P338,P337+P313P
H335 Kann die Atemwege reizen. Spezifische Zielorgan-Toxizit?t (einmalige Exposition) Kategorie 3 (Atemwegsreizung) Warnung GHS hazard pictogramssrc="/GHS07.jpg" width="20" height="20" />
Sicherheit
P261 Einatmen von Staub vermeiden.
P305+P351+P338 BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen.

2,3-Didehydro-D-erythro-hexono-1,4-lacton Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Chemische Eigenschaften

Erythorbic acid occurs as a white or slightly yellow-colored crystals or powder. It gradually darkens in color upon exposure to light.

Verwenden

Erythorbic Acid is a food preservative that is a strong reducing agent (oxygen accepting) which functions similarly to antioxidants. In the dry crystalline state it is nonreactive, but in water solutions it reacts readily with atmospheric oxygen and other oxidizing agents, making it valuable as an antioxidant. During preparation, dissolving and mixing should incorporate a minimum amount of air, and storage should be at cool temperatures. It has a solubility of 43 g/100 ml of water at 25°c. One part is equivalent to one part ascorbic acid and equivalent to one part sodium erythorbate. It is used to control oxidative color and flavor deterioration in fruits at 150–200 ppm. It is used in meat curing to speed and control the nitrite curing reaction and prolong the color of cured meat at levels of 0.05%.

Vorbereitung Methode

Erythorbic acid is synthesized by the reaction between methyl 2- keto-D-gluconate and sodium methoxide. It can also be synthesized from sucrose, and produced from Penicillium spp.

Pharmazeutische Anwendungen

Erythorbic acid is a stereoisomer of L-ascorbic acid, and is used as an antioxidant in foods and oral pharmaceutical formulations. It has approximately 5% of the vitamin C activity of L-ascorbic acid.

Sicherheit(Safety)

Erythorbic acid is widely used in food applications as an antioxidant. It is also used in oral pharmaceutical applications as an antioxidant. Erythorbic acid is generally regarded as nontoxic and nonirritant when used as an excipient. Erythorbic acid is readily metabolized and does not affect the urinary excretion of ascorbic acid.
The WHO has set an acceptable daily intake of erythorbic acid and its sodium salt in foods at up to 5 mg/kg body-weight.

Solubility in organics

40% soluble in water. Soluble in alcohol, slightly soluble in Glycerin and Propylene glycol.

Lager

Erythorbic acid should be stored in an airtight container, protected from light, in a cool, dry place.

l?uterung methode

Crystallise D(-)-isoascorbic acid from H2O, EtOH or dioxane. is at 245nm with 7,500 (EtOH). [Reichstein et al. Helv max Chim Acta 17 510, 516 1934, Heslop et al. J Chem Soc 225 1944, Beilstein 18 III/IV 3037, 18/5 V 26.]

Inkompatibilit?ten

Erythorbic acid is incompatible with chemically active metals such as aluminum, copper, magnesium, and zinc. It is also incompatible with strong bases and strong oxidizing agents.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral concentrate and tablets).

2,3-Didehydro-D-erythro-hexono-1,4-lacton Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


2,3-Didehydro-D-erythro-hexono-1,4-lacton Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 535)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Nanjing Sky Hope Tongyuan Biological Engineering Co., Ltd.
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89-65-6(2,3-Didehydro-D-erythro-hexono-1,4-lacton)Verwandte Suche:


  • FEMA 2410
  • ISOVITAMIN C
  • 3-keto-d-erythro-hexonicacigamma-lactone
  • d-erythro-3-ketohexonicacidlactone
  • D-Erythro-3-ketohex-onicacidlactone
  • d-erythro-3-oxohexonicacidlactone
  • d-erythro-ascorbicacid
  • erythro-Hex-2-enonicacid,1,4-lactone
  • femanumber:2410
  • glucosaccharonicacid
  • mercate"5"
  • mercate5
  • D-(-)-ARABOASCORBIC ACID
  • D-ERYTHRO-3-KETOHEXANOIC ACIDLACTONE
  • D-ERYTHRO-3-OXOHEXANOIC ACID LACTONE
  • D-Erythro-hex-2-enonic acid
  • D-ERYTHRO-HEX-2-ENONIC ACID, GAMMA-LACTONE
  • D-(-)-ERYTHORBIC ACID
  • D-ERYTHORBIC ACID
  • ERYCORBIN
  • ERYTHORBIC ACID
  • D(-)-ISOASCORBIC ACID
  • SACCHAROSONIC ACID
  • NEOCEBICURE
  • D-erythro-Hex-2-enoic acid γ-lactone
  • D-ISOASCORBIC ACID 99+% FCC
  • D-IsoascorbicAcid,>99%
  • ERYTHORBICACID,FCC
  • D-(-)-ARABOASCORBICACID(ERYTHORBICACID)
  • Araboascorbic acid, D-
  • D-erythro-Hex-2-enonic acid, γ-lactone (8CI, 9CI)
  • D-erythro-Hexonic acid, 3-keto-, γ-lactone (6CI)
  • D-erythro-Hex-2-enoic acid γ-lactone D-Araboascorbic acid D-Erythorbic Acid
  • Erythorbic acid (7CI)
  • NSC 8117
  • D-ASCORBICACID
  • D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid
  • D-(-)-Isoascorbic acid, D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid, Erythorbic acid
  • (R)-5-[(R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one
  • 3,4-Dihydroxy-5β-[(R)-1,2-dihydroxyethyl]-2(5H)-furanone
  • D(-)-Isoascorbic acid,98%
  • D-()-Isoascorbic acid,D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid
  • D-Isoascorbic acid,D-()-Isoascorbic acid, D-erythro-Hex-2-enoic acid γ-lactone, D-Araboascorbic acid, Erythorbic acid
  • )-Isoascor
  • Erythorbic Acid (50 mg)
  • D-()-Isoascor
  • D(-)-Isoascorbic acid, 98% 100GR
  • D(-)-Isoascorbic acid, 98% 500GR
  • Erythorbic Acid API
  • D-Erythorbic Acid D-Isoascorbic Acid
  • D-(-)-Isoascorbic acid 98%
  • D(-)-Isoascorb
  • Erthorbic Acid
  • -3,4-dihydroxyfuran-2(5H)
  • D-Isoascorbic acid
  • (2R)-2-[(1R)-1,2-dihydroxyethyl]-3,4-dihydroxy-2H-furan-5-one
  • Ascorbic Acid Impurity 6(Ascorbic Acid EP Impurity F)
  • sodium 5-(1,2-dihydroxyethyl)-3-hydroxyfuran-3-ide-2,4-dione
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