D-Glucose, 6-(Dihydrogen-phosphat), Mononatriumsalz
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- CAS-Nr.
- 54010-71-8
- Bezeichnung:
- D-Glucose, 6-(Dihydrogen-phosphat), Mononatriumsalz
- Englisch Name:
- ROBISON ESTER MONOSODIUM SALT
- Synonyma:
- G6P sodium salt;Einecs 258-921-0;D-Glucose 6-phosphat;Sodium (2R,3R,4S,5R);G-6-P Na, Robison ester;Sodium Glucose-6-Phosphate;a-D-Glucose-6-Phosphate, Na;D-Glucose 6-phosphate sodium;ROBISON ESTER MONOSODIUM SALT;D-Glucose6-phosphatesodiumsal
- CBNumber:
- CB3681824
- Summenformel:
- C6H14NaO9P
- Molgewicht:
- 284.13
- MOL-Datei:
- 54010-71-8.mol
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D-Glucose, 6-(Dihydrogen-phosphat), Mononatriumsalz Eigenschaften
- Schmelzpunkt:
- 204 °C (dec.)(lit.)
- storage temp.
- Sealed in dry,Room Temperature
- L?slichkeit
- H2O: 50 mg/mL, clear, colorless to very faintly yellow
- Aggregatzustand
- crystalline
- BRN
- 5787568
- InChI
- InChI=1/C6H13O9P.Na.H/c7-1-3(8)5(10)6(11)4(9)2-15-16(12,13)14;;/h1,3-6,8-11H,2H2,(H2,12,13,14);;/t3-,4+,5+,6+;;/s3
- InChIKey
- RUFPTDNHMAGVMV-IWNCBHIWNA-N
- SMILES
- [C@@H](O)([C@H](O)COP(O)(O)=O)[C@H](O)[C@@H](O)C=O.[NaH] |&1:0,2,10,12,r|
- CAS Datenbank
- 54010-71-8(CAS DataBase Reference)
D-Glucose, 6-(Dihydrogen-phosphat), Mononatriumsalz Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
Beschreibung
D-Glucose-6-phosphate is formed in cells when glucose is phosphorylated by hexokinase (or glucokinase) or by the conversion of glucose-1-phosphate by phosphoglucomutase, which is the first step of glycogen synthesis. It is stored as glycogen when blood glucose levels are high. Disruption of D-glucose-6-phosphate activity leads to glycogen storage disease type I or von Gierke’s disease, a group of inherited metabolic diseases characterized by severe hypoglycemia, growth retardation, and hepatomegaly, due to accumulation of glycogen and fat in the liver. D-Glucose-6-phosphate is also the starting molecule of both glycolysis and the pentose phosphate pathways. Because cancer cells adopt glycolysis as a major source of metabolic energy production, and the pentose phosphate pathway plays a role in helping glycolytic cancer cells to meet their anabolic demands, this compound can be used to study the progression of this process.
Chemische Eigenschaften
White crystalline solid
Allgemeine Beschreibung
A glycolytic intermediate that also acts as a competitive and reversible inhibitor of hexokinase. Useful in creating an ATP-regenerating system. Causes the release of mitochondrially bound hexokinase in muscle.
l?uterung methode
It can be freed from metal impurities as described for glucose-1-phosphate. The solubility of the Na salt is 5% in H2O at 20o. Its barium salt can be purified by solution in dilute HCl and precipitation by neutralising the solution. The precipitate is washed with small volumes of cold water and dried in air. Alternatively the barium salt is dissolved in H2O, 4volumes of EtOH are added, the precipitate is collected, washed with 90% EtOH, absolute EtOH, 75% EtOH/25% Et2O, 25% EtOH/75% Et2O and finally dry Et2O. The dry Barium salt has [] D +17.9o (c 1, H2O). [Beilstein 1 IV.]
D-Glucose, 6-(Dihydrogen-phosphat), Mononatriumsalz Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
D-Glucose, 6-(Dihydrogen-phosphat), Mononatriumsalz Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 195)Lieferanten
54010-71-8(D-Glucose, 6-(Dihydrogen-phosphat), Mononatriumsalz)Verwandte Suche:
- ROBISON ESTER MONOSODIUM SALT
- beta-d-glucose6-phosphatesodiumsaltanhydrous
- BETA-D-GLUCOSE 6-PHOSPHATE MONOSODIUM SALT
- D(+)-GLUCOPYRANOSE 6-PHOSPHATE MONOSODIUM SALT
- D-GLUCOSE 6-PHOSPHATE MONOSODIUM SALT
- D(+)-Glucopyranose 6-phosphate sodium salt
- D-Glucose 6-phosphate sodium salt
- a-D-Glucose-6-Phosphate, Na
- d-Glucose, 6-(dihydrogen phosphate), monosodium salt
- D-GLUCOSE 6-PHOSPHATE MONOSODIUM*SIGMA G RADE
- BETA-D-GLUCOSE 6-PHOSPHATE MONOSODIUM SALT ANHYDROUS
- b-D-Glucose 6-phosphate sodium salt
- D(+)-Glucopyranose 6-phosphate sodium salt, G-6-P Na, Robison ester
- D-Glucose 6-phosphoric acid hydrogen sodium salt
- G-6-P Na, Robison ester
- Einecs 258-921-0
- SodiuM (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl hydrogenphosphate
- D-Glucose6-phosphate Sodium sslt
- D-Glucose 6-phosphate sodium salt solution
- D-Glucose 6-phosphate sodium salt,D(+)-Glucopyranose 6-phosphate sodium salt, G-6-P Na, Robison ester
- D-Glucose 6-phosphat
- D-Glucose-6-phosphate monosodium salt ,98%
- D-GLUCOSE 6-PHOSPHATE SODIUM SALT(2-8℃)
- -2,3,4,5-tetrahydroxy-6-oxohexyl hydrogenphosphate
- Sodium (2R,3R,4S,5R)
- α-D-Glucose-6-phosphate, Monosodium Salt - CAS 54010-71-8 - Calbiochem
- D-Glucose 6-phosphate sodium
- D-Glucose 6-phosphate sodium salt, 97%, reagent grade
- G6P sodium salt
- Sodium Glucose-6-Phosphate
- ROBISON ESTER MONOSODIUM SALT USP/EP/BP
- β-D-Glucose 6-phosphate sodium salt
- D-Glucose6-phosphatesodiumsal
- 54010-71-8
- C6H12O9PNa
- Carbohydrate Synthesis
- Metabolomics
- Metabolic Pathways
- Metabolites and Cofactors on the Metabolic Pathways Chart
- Monosaccharides
- Monosaccharide
- Specialty Synthesis
- BioChemical
- Biochemicals and Reagents
- Carbohydrate
- Carbohydrates
- substrate
- Substrates
- Dextrins、Sugar & Carbohydrates
