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MAGAININ II

MAGAININ II Struktur
108433-95-0
CAS-Nr.
108433-95-0
Englisch Name:
MAGAININ II
Synonyma:
MAGAININ 2;Aids007842;MAGAININ II;Aids-007842;Magainin II peptide;MAGAININ II USP/EP/BP;GIGKFLHSAKKFGKAFVGEIMNS;Magainin II, ≥97% (HPLC);Magainin 2 (Xenopus laevis);Magainin 2 peptide, Xenopus
CBNumber:
CB3664319
Summenformel:
C114H180N30O29S
Molgewicht:
2466.9
MOL-Datei:
108433-95-0.mol

MAGAININ II Eigenschaften

Siedepunkt:
2444.0±65.0 °C(Predicted)
Dichte
1.275±0.06 g/cm3(Predicted)
storage temp. 
-20°C
L?slichkeit
Soluble in DMSO
Aggregatzustand
Solid
Farbe
White to off-white
Sequenz
H-Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH

Sicherheit

WGK Germany  3

MAGAININ II Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

Magainin II is a member of the antimicrobial peptides family. It is a cationic peptide with Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser amino acid sequence. Magainin II is water soluble and non-hemolytic at its effective and amphiphilic antimicrobial concentrations.

Biochem/physiol Actions

Magainin II acts as an antibiotic in a variety of organisms. Magainin II exhibits cytotoxic and anti-proliferative effects via pore formation in bladder cancer cells. In mice, it acts as an anti-tumor agent in several cancer cell lines and tumors. Magainin II facilitates lactate dehydrogenase discharge from mammalian cells. It directly interacts with certain cell membranes via amphiphilic α-helix and forms permeable ion channels, which results in depolarization and irreversible cytolysis and finally cell death. At low concentrations, Magainin II retards the growth of bacterial and fungal species and it promotes cytolysis in protozoa.

MAGAININ II Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


MAGAININ II Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 109)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Zibo Hangyu Biotechnology Development Co., Ltd
+86-0533-2185556 +8617865335152
Mandy@hangyubiotech.com China 10986 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715
admin@nexconn.com China 10311 58
Cellmano Biotech Limited
0551-65326643 18156095617
info@cellmano.com China 999 58
career henan chemical co
+86-0371-86658258 +8613203830695
factory@coreychem.com China 29811 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22784 58
BOC Sciences
16314854226; +16314854226
inquiry@bocsci.com United States 19741 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
Hangzhou Go Top Peptide Biotech
0571-88211921
sales1@gotopbio.com CHINA 2609 58
Chengdu Youngshe Chemical Co., Ltd.
+8618108235634
Cecilia@youngshechem.com China 2345 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58

  • H-GLY-ILE-GLY-LYS-PHE-LEU-HIS-SER-ALA-LYS-LYS-PHE-GLY-LYS-ALA-PHE-VAL-GLY-GLU-ILE-MET-ASN-SER-OH
  • GLY-ILE-GLY-LYS-PHE-LEU-HIS-SER-ALA-LYS-LYS-PHE-GLY-LYS-ALA-PHE-VAL-GLY-GLU-ILE-MET-ASN-SER
  • GIGKFLHSAKKFGKAFVGEIMNS
  • MAGAININ II
  • MAGAININ 2
  • 96: PN: WO2009015163 SEQID: 98 unclaimed protein
  • Magainin 2 (Xenopus laevis)
  • Magainin II peptide
  • WO2011023702 SEQID: 10 claimed protein
  • Gly-Ile-Gly-Lys-Phe-Leu-His-Ser-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Gly-Glu-Ile-Met-Asn-Ser-OH
  • Gly-L-Ile-Gly-L-Lys-L-Phe-L-Leu-L-His-L-Ser-L-Ala-L-Lys-L-Lys-L-Phe-Gly-L-Lys-L-Ala-L-Phe-L-Val-Gly-L-Glu-L-Ile-L-Met-L-Asn-L-Ser-OH
  • Aids007842
  • Aids-007842
  • Magainin 2 peptide, Xenopus
  • Magainin II, ≥97% (HPLC)
  • Magainin I, 10-L-lysine-22-L-asparagine-
  • MAGAININ II USP/EP/BP
  • 108433-95-0
  • C114H180N30O29S
  • C114H180N30O29S1
  • Cell Biology
  • BioChemical
  • Cell Signaling and Neuroscience
  • Immune Cell Signaling and Blood
  • Immune System Regulation
  • Immunomodulators and Antibiotics
  • Peptide
  • Immunomodulators and AntibioticsAntibiotics
  • Antibiotic PeptidesImmune Cell Signaling and Blood
  • Chemical Structure Class
  • Immune System Regulation
  • Immunomodulators
  • Interferes with Cell Membrane Permeability (Ionophores)Antibiotics
  • Mechanism of Action
  • Peptides
  • Peptides for Cell Biology
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