Histone H3K9Me2 Polyclonal Antibody Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei. It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination. Dimethylation of histone H3 at lysine 9 (H3K9Me2) is associated with transcriptional repression. Heterochromatin protein 1-α (HP1-α), HP1-β, and HP1-γ selectively bind histone H3 N-terminal peptides containing dimethylated lysine 9 over unmodified lysine 9. High nuclear levels of H3K9Me2 in tumor tissue are associated with decreased disease-specific and disease-free survival in patients with oral and oropharyngeal squamous cell carcinoma. Cayman’s Histone H3K9Me2 Polyclonal Antibody can be used for ELISA.
Histone H3K9Me2 Polyclonal Antibody Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
