ANTI HUMAN TR-ALPHA
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- CAS-Nr.
- Englisch Name:
- ANTI HUMAN TR-ALPHA
- Synonyma:
- GRTH;THB1;THR1;EAR7;ERBA2;THRB1;NR1A2;EAR-7;ERBA1;NR1A1
- CBNumber:
- CB3416653
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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ANTI HUMAN TR-ALPHA Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- buffered aqueous glycerol solution
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
ANTI HUMAN TR-ALPHA Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-THRA antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project
(www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these
protocols and other useful information about Prestige Antibodies and the HPA, visit .
Allgemeine Beschreibung
THRA (thyroid hormone receptor α) belongs to a family of nuclear receptors, which function as ligand-regulated transcription factors and are called thyroid hormone receptors (TRs). THRA is a predominant mammalian TR isoform. This receptor is highly expressed in central nervous system, myocardium, gastrointestinal tract and skeletal muscle.
Biochem/physiol Actions
Conserved lysine in the DNA-binding domain of this receptor functions as a sensor of transcriptional regulation. This lysine is mutated in hepatocellular carcinoma (HCC). Mutations in this protein result in resistance to thyroid hormone, which is alleviated by thyroxine treatment. Population with rs939348 TT polymorphism in this gene show weak relation to increased risk to Alzheimer′s disease. This receptor is also up-regulated in patients with breast cancer.
ANTI HUMAN TR-ALPHA Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
ANTI HUMAN TR-ALPHA Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 4)Lieferanten
- Anti-Nuclear receptor subfamily 1 group A member 1
- Anti-c-erbA-1
- Anti-C-erbA-alpha
- Anti-EAR7
- Anti-EAR-7
- Anti-THRA antibody produced in rabbit
- ERBA-beta
- GRTH
- THRB1
- TR, β 1 isoform human
- ERBA2
- NR1A2
- THB1
- THR1
- Anti-AR7
- Anti-THRA antibody produced in goat
- Anti-α-Erythroblastic leukemia viral (v-erb-a) oncogene homolog
- Anti- THRA2
- Anti-ERBA1
- Anti-ERB-T-1
- Anti-NR1A1
- Anti-THRA (176-190) antibody produced in rabbit
- Anti-Thyroid hormone receptor, α (erythroblastic leukemia viral (v-erb-a)
- Anti-Thyroid Hormone Receptor α, N-Terminal antibody produced in rabbit
- C-erbA-α
- EAR7
- EAR-7
- ERBA1
- NR1A1
- ANTI-THYROID HORMONE RECEPTOR ALPHA
- ANTI-TR ALPHA
- ANTI HUMAN TR-ALPHA
