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Glucosamin

Glucosamine Struktur
3416-24-8
CAS-Nr.
3416-24-8
Bezeichnung:
Glucosamin
Englisch Name:
Glucosamine
Synonyma:
D-GLUCOSAMINE;aminoglucose;2-amino-2-deoxy-d-glucose;2-amino-2-deoxy-d-glucos;GLUCOSAMINE;Glucosamine 13C6;D-(+)-Glucosamine hy;SYNTHETICGLUCOSAMINE;Propyl N-Acetyl-βGlucosamine USP/EP/BP
CBNumber:
CB3414563
Summenformel:
C6H13NO5
Molgewicht:
179.17
MOL-Datei:
3416-24-8.mol

Glucosamin Eigenschaften

Siedepunkt:
311.69°C (rough estimate)
Dichte
1.3767 (rough estimate)
Brechungsindex
1.4240 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
L?slichkeit
DMSO:23.0(Max Conc. mg/mL);128.37(Max Conc. mM)
Water:36.0(Max Conc. mg/mL);200.93(Max Conc. mM)
Aggregatzustand
Solid
pka
pKa 8.04(H2O,t = 15.5,I=0.00,N2)(Approximate)
Schmelzpunkt:
88 °C
Farbe
White to Off-White
Optische Aktivit?t
α form +100 → +72(HCl) β form +28 → +47.5
LogP
-2.175 (est)
CAS Datenbank
3416-24-8(CAS DataBase Reference)
EPA chemische Informationen
Glucosamine (3416-24-8)

Sicherheit

Giftige Stoffe Daten 3416-24-8(Hazardous Substances Data)

Glucosamin Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften

(β form.) Colorless needles. Mp 110C (decomposes). Very soluble in water; slightly soluble in methanol and ethanol; insoluble in ether and chloroform.

Occurrence

Glucosamine is found in mucopolysaccharides, chitin, and mucoproteins. Glucosamine is a naturally occurring substance; glucosamine sulfate is manufactured synthetically.

Verwenden

Glucosamine is an amino sugar that can regulate growth factor gene transcription. It is also widely touted as remedy for osteoarthritis (OA).

Definition

ChEBI: The open-chain form of D-glucosamine.

Weltgesundheitsorganisation (WHO)

Glucosamine is found in chitin, mucoproteins and mucopolysaccharides. It is used as a pharmaceutical aid. Glucosamine sulfate has been used in the treatment of rheumatic disorders though it is not widely marketed for this purpose.

l?uterung methode

Crystallise the amines from MeOH. The free base has been obtained from the hydrochloride (21.5g, see below) in a mixture of Et3N (15mL) and EtOH (125mL) by shaking for 2days at room temperature, and the solid Et3N.HCl is filtered off and the process repeated with more Et3N (3-4 times) until the D-glucosamine (15g) is free from Cl ions. It has m 88o , [] D20 +100o mutarotating to +47.5o (c 1, H2O). When Et2NH is used as base, the  to  conversion is complete giving D-glucosamine. The pentaacetate is purified by dissolving in CHCl3, treating with charcoal, drying (MgSO4), evaporating the solvent, and adding a little dry Et2O to induce crystallisation. It has m 124-126o, [] D +113o (c 1, CHCl3) after 16hours in a desiccator. [Leaback Biochemical Preparations 10 118 1963.] The N-acetyl derivative, m 203-205o from MeOH/Et2O (dry in vacuum P2O5) has [] D +75o to +41o (c 2, H2O); this derivative can also be purified by dissolving in the minimum volume of H2O to which is added 7-8volumes of EtOH followed by Et2O until turbid and keeping at ~20o to crystallise. Wash the crystals with MeOH then Et2O and dry in vacuo over P2O5. [Horton Biochemical Preparations 11 1 1966.]

Glucosamin Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Glucosamin Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 276)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Weibang Biotechnology Co., Ltd
+8615531157085
abby@weibangbio.com China 8810 58
Hebei Mojin Biotechnology Co., Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12835 58
Shaanxi Haibo Biotechnology Co., Ltd
+undefined18602966907
qinhe02@xaltbio.com China 997 58
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info@fdachem.com China 20284 58
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+86-16264648883 +86-16264648883
niki@zlchemi.com China 2691 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806
sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd.
+8615858145714
FandaChem@Gmail.com China 9087 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32957 60

3416-24-8(Glucosamin)Verwandte Suche:


  • 2-Amino-2-deoxyglucose
  • D-Glucose, 2-amino-2-deoxy-
  • SHRIMP-DERIVEDGLUCOSAMINE
  • SYNTHETICGLUCOSAMINE
  • 2-Amino-2-deoxy-beta-D-glucopyranose
  • 2-Amino-2-deoxy-α-D-glucopyranose
  • 2-Deoxy-2-amino-D-glucopyranose
  • D-(+)-Glucosamine hy
  • GlucosaMine(Feed grade)
  • D-Glucosamine(HCl form)
  • GLUCOSAMINE
  • aldehydo-D-glucosamine
  • D-Glucosamine (Free Base)
  • 2-hydroxy-3-(5-(morpholinomethyl)pyridin-2-yl)-1H-indole-5
  • Propyl N-Acetyl-&beta
  • Glucosamine USP/EP/BP
  • Glucosamine DISCONTINUED. See alternates.
  • Glucosamine 13C6
  • 2-amino-2-deoxy-d-glucos
  • 2-amino-2-deoxy-d-glucose
  • D-GLUCOSAMINE
  • aminoglucose
  • GLUCOSAMINE 25% GRANULES
  • Nicotinamide Impurity 126
  • 2-ammonio-2-deoxy-D-glucopyranose
  • Glucosamine Hydrochloride Impurity 37
  • 3416-24-8
  • 966-84-2
  • C6H14O5NCl
  • Inhibitors
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