MST-312
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- CAS-Nr.
- 368449-04-1
- Englisch Name:
- MST-312
- Synonyma:
- MST-312;MST-312 >=98% (HPLC);TELOMERASE INHIBITOR IX;N,N'-(1,3-Phenylene)bis(2,3-dihydroxybenzamide);Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-;N,N′-1,3-Phenylenebis-[2,3-dihydroxy-benzamide];N,N'-BIS(2,3-DIHYDROXYBENZOYL)-1,3-PHENYLENEDIAMINE;Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem;N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide;EGCG,Telomerase,epigallocatechin,gallate,Inhibitor,multiple,tea,MST-312,derivative,cancer,MST 312,inhibit,MST312,myeloma
- CBNumber:
- CB3366639
- Summenformel:
- C20H16N2O6
- Molgewicht:
- 380.35
- MOL-Datei:
- 368449-04-1.mol
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MST-312 Eigenschaften
- Siedepunkt:
- 526.7±50.0 °C(Predicted)
- Dichte
- 1.578±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: ≥20mg/mL
- Aggregatzustand
- White solid
- pka
- 7.70±0.35(Predicted)
- Farbe
- off-white to light tan
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Kennzeichnung gef?hrlicher |
N |
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| R-S?tze: |
50 |
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| S-S?tze: |
61 |
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| WGK Germany |
2 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H400 |
Sehr giftig für Wasserorganismen. |
Kurzfristig (akut) gew?ssergef?hrdend |
Kategorie 1 |
Warnung |
![GHS hazard pictograms]() src="/GHS09.jpg" width="20" height="20" /> |
P273, P391, P501 |
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| Sicherheit |
| P273 |
Freisetzung in die Umwelt vermeiden. |
| P391 |
Verschüttete Mengen aufnehmen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
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MST-312 Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
MST-312 has been used in cell invasion assay using mouse fibroblast cells (NIH-3T3) and in the co-immunoprecipitation experiments in colon fibroblast.
Allgemeine Beschreibung
A cell-permeable, bis-catechol containing,
m-phenylenediamide compound that displays anti-proliferative properties. Acts as a potent, reversible inhibitor of telomerase activity (IC
50 = 670 nM, TRAP lysate prepared from U937 cells). Prolonged treatment with MST-312 has been reported to result in telomere shortening and growth arrest in U937 cells. Does not inhibit the activity of Taq DNA polymerase (IC
50 >3 μM).
Biochem/physiol Actions
Cell permeable: yes
MST-312 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
MST-312 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 26)Lieferanten
- TELOMERASE INHIBITOR IX
- MST-312
- N,N'-BIS(2,3-DIHYDROXYBENZOYL)-1,3-PHENYLENEDIAMINE
- N,N′-1,3-Phenylenebis-[2,3-dihydroxy-benzamide]
- Telomerase Inhibitor IX - CAS 368449-04-1 - Calbiochem
- N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide
- Benzamide, N,N'-1,3-phenylenebis[2,3-dihydroxy-
- MST-312 >=98% (HPLC)
- EGCG,Telomerase,epigallocatechin,gallate,Inhibitor,multiple,tea,MST-312,derivative,cancer,MST 312,inhibit,MST312,myeloma
- N,N'-(1,3-Phenylene)bis(2,3-dihydroxybenzamide)
- 368449-04-1
