DIHYDROMETHYSTICIN
|
|
|
- CAS-Nr.
- 19902-91-1
- Englisch Name:
- DIHYDROMETHYSTICIN
- Synonyma:
- dhm;Nsc112159;PseudoMethysticin;DIHYDROMETHYSTICIN;DIHYDROMETHYLSTICIN;Dihydromethysticin-RM;7,8-dihydromethysticin;7,8-DIHYDROMETHYLSTICIN;Methysticin, 7,8-dihydro-;Dihydroanesthetic capsicin
- CBNumber:
- CB3307966
- Summenformel:
- C15H16O5
- Molgewicht:
- 276.28
- MOL-Datei:
- 19902-91-1.mol
|
DIHYDROMETHYSTICIN Eigenschaften
- storage temp.
- 2-8°C
- L?slichkeit
- Chloroform (Slightly), Methanol (Slightly), Pyridine (Slightly)
- Siedepunkt:
- 476.1±45.0 °C(Predicted)
- Dichte
- 1.28±0.1 g/cm3(Predicted)
- Schmelzpunkt:
- 117-118 °C
- Aggregatzustand
- Solid
- Farbe
- White to Off-White
- BRN
- 91699
- Stabilit?t:
- Hygroscopic
- InChIKey
- RSIWXFIBHXYNFM-NSHDSACASA-N
- LogP
- 1.810 (est)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
|
| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
|
| Sicherheit |
| P264 |
Nach Gebrauch gründlich waschen. |
| P264 |
Nach Gebrauch gründlich waschen. |
| P270 |
Bei Gebrauch nicht essen, trinken oder rauchen. |
| P301+P312 |
BEI VERSCHLUCKEN: Bei Unwohlsein GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P330 |
Mund ausspülen. |
| P501 |
Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen. |
|
DIHYDROMETHYSTICIN Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
Dihydromethysticin is a kavalactone originally isolated from
P. methysticum (kava-kava) that has diverse biological activities, including efflux transporter inhibitory, antinociceptive, and neuroprotective properties. Dihydromethysticin is a P-glycoprotein (P-gp) inhibitor that increases uptake of the P-gp substrate calcein AM by 50% in P388 mouse leukemia cancer cells overexpressing P-gp when used at a concentration of 54.6 μM. Dihydromethysticin (275 mg/kg) has analgesic activity, increasing the latency to tail withdrawal in the tail-flick assay in mice. It also decreases the infarct size in a mouse model of ischemia induced by microbipolar coagulation of the left middle cerebral artery (MCA) when administered at a dose of 10 mg/kg.
DIHYDROMETHYSTICIN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
DIHYDROMETHYSTICIN Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 128)Lieferanten
19902-91-1()Verwandte Suche:
- 6-(2-(1,3-benzodioxol-5-yl)ethyl)-5,6-dihydro-4-methoxy-2h-pyran-2-on(s)
- 6-dihydro-4-methoxy-6-(3,4-(methylenedioxy)phenethyl)-(s)-2h-pyran-2-on
- 7,8-dihydromethysticin
- dhm
- DIHYDROMETHYLSTICIN
- 7,8-DIHYDROMETHYLSTICIN
- 5,6-Dihydro-4-methoxy-6-[2-(1,3-benzodioxol-5-yl)ethyl]-2H-pyran-2-one
- 6-[2-(1,3-Benzodioxol-5-yl)ethyl]-4-methoxy-5,6-dihydro-2H-pyran-2-one
- 2H-Pyran-2-one, 5,6-dihydro-4-methoxy-6-[3,4-(methylenedioxy)phenethyl]-, (S)-
- 2H-Pyran-2-one, 6-[2-(1,3-benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-, (S)-
- Methysticin, 7,8-dihydro-
- Nsc112159
- PseudoMethysticin
- (6S)-6-[2-(1,3-Benzodioxol-5-yl)ethyl]-5,6-dihydro-4-Methoxy-2H-pyran-2-one
- DIHYDROMETHYSTICIN
- Dihydromethysticin ((+)-Dihydromethysticin)
- 2H-Pyran-2-one, 6-[2-(1,3-benzodioxol-5-yl)ethyl]-5,6-dihydro-4-methoxy-, (6S)-
- Dihydromethysticin,Inhibitor,inhibit,CYPs,Cytochrome P450
- (S)-6-(2-(Benzo[d][1,3]dioxol-5-yl)ethyl)-4-methoxy-5,6-dihydro-2H-pyran-2-one
- Dihydroanesthetic capsicin
- Dihydromethysticin-RM
- 19902-91-1
- Coumarins
