3-β,17-α-Dihydroxypregn-5-en-20-on
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- CAS-Nr.
- 387-79-1
- Bezeichnung:
- 3-β,17-α-Dihydroxypregn-5-en-20-on
- Englisch Name:
- 17ALPHA-HYDROXYPREGNENOLONE
- Synonyma:
- NSC 63853;17-OH PREG;17alpha-Hydroxy;17-OH Pregnenolone;Dronedarone HCl-d6;Hydroxypregnenolone;17a-Hydroxypregnolone;17A-HYDROXYPREGENOLONE;17-HYDROXYPREGNENOLONE;17α-Hydroxypregnenolone
- CBNumber:
- CB3175435
- Summenformel:
- C21H32O3
- Molgewicht:
- 332.48
- MOL-Datei:
- 387-79-1.mol
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3-β,17-α-Dihydroxypregn-5-en-20-on Eigenschaften
- Schmelzpunkt:
- 273℃
- Flammpunkt:
- 9℃
- storage temp.
- -20°C
- L?slichkeit
- Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated)
- Aggregatzustand
- Solid
- Siedepunkt:
- 478.4±45.0 °C(Predicted)
- Dichte
- 1.15±0.1 g/cm3(Predicted)
- pka
- 13.02±0.70(Predicted)
- Farbe
- White to Off-White
- CAS Datenbank
- 387-79-1(CAS DataBase Reference)
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| Bildanzeige (GHS) |
  
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| Alarmwort |
Achtung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H225 |
Flüssigkeit und Dampf leicht entzündbar. |
Entzündbare Flüssigkeiten |
Kategorie 2 |
Achtung |
![GHS hazard pictograms]() src="/GHS02.jpg" width="20" height="20" /> |
P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501 |
| H370 |
Sch?digt die Organe. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 1 |
Achtung |
![GHS hazard pictograms]() src="/GHS08.jpg" width="20" height="20" /> |
P260, P264, P270, P307+P311, P321,P405, P501 |
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| Sicherheit |
| P210 |
Von Hitze, hei?en Oberfl?chen, Funken, offenen Flammen und anderen Zündquellenarten fernhalten. Nicht rauchen. |
| P260 |
Dampf/Aerosol/Nebel nicht einatmen. |
| P280 |
Schutzhandschuhe/Schutzkleidung/Augenschutz tragen. |
| P301+P310 |
BEI VERSCHLUCKEN: Sofort GIFTINFORMATIONSZENTRUM/Arzt/... (geeignete Stelle für medizinische Notfallversorgung vom Hersteller/Lieferanten anzugeben) anrufen. |
| P311 |
GIFTINFORMATIONSZENTRUM/Arzt anrufen. |
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3-β,17-α-Dihydroxypregn-5-en-20-on Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
17α-hydroxy Pregnenolone is a metabolite of pregnenolone and a precursor in the biosynthesis of dehydroepiandrosterone (DHEA; ). It is formed from pregnenolone by cytochrome P450 (CYP) isoform CYP17A1 hydroxylase activity and then converted to dehydroepiandrosterone by CYP17A1-mediated 17,20-lyase activity. Plasma levels of 17α-hydroxy pregnenolone are elevated in patients with type II 3β-hydroxysteroid dehydrogenase deficiency, a form of congenital adrenal hyperplasia.
Verwenden
17α-hydroxypregnenolone has been used as a substrate for the enzyme 3β‐hydroxysteroid dehydrogenase (3β‐HSD) expressed in COS1 cells.
Allgemeine Beschreibung
17α-hydroxypregnenolone is a derived from pregnenolone.
3-β,17-α-Dihydroxypregn-5-en-20-on Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Androst-5-ene-17-carbonitrile, 3-(acetyloxy)-17-hydroxy-, (3β,17α)- (9CI)
Pregn-5-en-20-one, 3-(acetyloxy)-16-bromo-17-hydroxy-, (3β)- (9CI)
Pregn-5-en-20-one, 17-hydroperoxy-3-hydroxy-, (3β)- (9CI)
Pregn-5-en-20-one,16-bromo-3,17-dihydroxy-, (3b,16b)- (9CI)
3-β,17-α-Dihydroxypregn-5-en-20-on-3-acetat
16-α,17-α-Epoxy-3-β-hydroxypregn-5-en-20-on
3,17-DIHYDROXY-PREGNA-3,5-DIEN-20-ONE DIACETATE
17-ACETOXYPREGNENOLONE
20-Oxopregna-5,16-dien-3-β-ylacetat
Pregnenolon
Hydroxyprogesteron
Downstream Produkte
3-β,17-α-Dihydroxypregn-5-en-20-on Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 97)Lieferanten
387-79-1(3-β,17-α-Dihydroxypregn-5-en-20-on)Verwandte Suche:
- 17alpha-Hydroxy
- (3b)-3,17-dihydroxy-Pregn-5-en-20-one
- 17a-Hydroxypregnolone
- 17ALPHA-LPHA-HYDROXYPREGNENOLONE
- 5-Pregnen-3b,17-dihydroxy-3-one
- 3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
- 17-OH PREG
- 17-OH Pregnenolone
- 3β,17-Dihydroxypregn-5-en-20-one
- 3β,17α-Dihydroxypregn-5-en-20-one
- 3-beta,17-dihydroxypregn-5-en-20-one
- 3-beta,17-alpha-dihydroxypregn-5-en-20-one
- Hydroxypregnenolone
- 17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H ASSAY ASSAY CHARACTERISTICS
- 17ALPHA-LPHA-HYDROXYPREGNENOLONE (1,2-3 H)
- 17ALPHA-LPHA-HYDROXYPREGNENOLONE 3H RIA KIT ASSAY CHARACTERISTICS
- 17ALPHA-LPHA-HYDROXYPREGNENOLONE CRYSTALLINE
- 17α-Hydroxypregnenolone,3β,17α-Dihydroxy-5-pregnen-20-one, 5-Pregnene-3β,17α-diol-20-one
- NSC 63853
- 3β,17α-Dihydroxy-5-pregnen-20-one
- 5-Pregnene-3β,17α-diol-20-one
- 17α-Hydroxypregnenolone solution
- 17α-hydroxypregnenolone solution,100ppm
- 3B 17A-DIHYDROXYPREGN-5-EN-20-ONE
- 3BETA,17ALPHA-DIHYDROXY-DELTA5-PREGNEN-20-ONE
- 3BETA,17ALPHA-DIHYDROXY-5-PREGNEN-20-ONE
- 3-BETA,17-DIHYDROXY-5-PREGNEN-3-ONE
- 5-PREGNENE-3BETA,17ALPHA-DIOL-20-ONE
- 5-PREGNEN-3-BETA, 17-DIOL-20-ONE
- 5-PREGNEN-3BETA-17A-DIOL-20-ONE
- 5-PREGNEN-3BETA,17ALPHA-DIOL-20-ONE
- 17-dihydroxy-(3-beta)-pregn-5-en-20-on
- 3-beta,17-dihydroxy-pregn-5-en-20-on
- HYDROXYPREGNENOLONE, 17A-
- 17A-HYDROXYPREGENOLONE
- 17A-HYDROXY PREGNENOLONE
- 17ALPHA-HYDROXYPREGNENOLONE
- 17-HYDROXYPREGNENOLONE
- Pregn-5-en-20-one, 3,17-dihydroxy-, (3β)-
- 17alpha-Hydroxypregnenolone-20,21-13C2,16,16-d2
- 17α-Hydroxypregnenolone
- 3b,17-Dihydroxy-5-pregnen-20-one
- 17α-Hydroxypregnenolone (Solution)
- "17A-HYDROXY PREGNENOLONE 13C2,D2"
- Inhibitor,17a Hydroxypregnenolone,Endogenous Metabolite,17aHydroxypregnenolone,inhibit,17a-Hydroxypregnenolone
- Dronedarone HCl-d6
- 5-PREGNEN-3β, 17-DIOL-20-ONE
- 17α-Hydroxypregnenolone-[13C2,d2] in Methanol
- 17α-Hydroxypregnenolone in Methanol
- 387-79-1
- Steroids
