E COLI ENDONUCLEASE III Chemische Eigenschaften,Einsatz,Produktion Methoden

Biochem/physiol Actions

Endo III, product of the nth gene, is an iron-sulfur containing DNA repair enzyme. It possesses DNA glycosylase activity with broad substrate specificity for mutated pyrimidine derivatives especially thymine glycol (Tg) but also for 5-hydroxycytosine and 5,6-dihydrothymine. In addition, it has an apurinic/apyrimidinic (AP) lyase activity which cleaves the DNA backbone by β elimination. Endo III protects E. coli cells from radiation damage caused by x-ray and UV irradiation and its activity overlaps the activity of endonuclease VIII. When overexpressed, it can also protect E.coli cells from alkylation defects caused by methylmethanesulphonate.

E COLI ENDONUCLEASE III Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

E COLI ENDONUCLEASE III Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80

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• NTH PROTEIN
• THYMINE GLYCOL-DNA GLYCOSYLASE
• E COLI NTH PROTEIN
• E COLI ENDONUCLEASE III
• ENDO III
• ENDONUCLEASE III
• Endonuclease III from Escherichia coli
• Enzymes, Inhibitors, and Substrates
• Biochemicals and Reagents
• Application Index
• BioChemical
• Cell Stress and Refolding
• Cell Signaling Enzymes