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dCBP-1

dCBP-1 Struktur
2484739-25-3
CAS-Nr.
2484739-25-3
Englisch Name:
dCBP-1
Synonyma:
dCBP-1;Inhibitor,p300,multiple,CRBN,myeloma,cell,degrader,PROTACs,MYC,CBP,inhibit,dCBP 1,dCBP1,heterobifunctional,Epigenetic Reader Domain,dCBP-1;3-(7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(1-(1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oyl)piperidin-4-yl)-N-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide;5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1-[1-[15-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-4-piperidinyl]-1,4,6,7-tetrahydro-N-methyl-
CBNumber:
CB28383268
Summenformel:
C51H63F2N11O10
Molgewicht:
1028.11
MOL-Datei:
2484739-25-3.mol

dCBP-1 Eigenschaften

Dichte
1.47±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C, sealed storage, away from moisture and light
L?slichkeit
DMSO : 50 mg/mL (48.63 mM; ultrasonic and warming and heat to 80°C)
Aggregatzustand
Solid
pka
10.80±0.40(Predicted)
Farbe
Light yellow to yellow
InChIKey
ILVRLRGBSSFKIE-UHFFFAOYSA-N
SMILES
C1N(C(NC)=O)CCC2N(C3CCN(C(=O)CCOCCOCCOCCOCCNC4C=CC5=C(C=4)C(=O)N(C4CCC(=O)NC4=O)C5=O)CC3)N=C(N3C4=C(C=C(C5=CN(C)N=C5)C(C(F)F)=C4)CCC3)C1=2

Sicherheit

dCBP-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

dCBP-1 is exceptionally potent at killing multiple myeloma cells and can abolish the enhancer that drives MYC oncogene expression. As an efficient degrader of this unique class of acetyltransferases, dCBP-1 is a useful tool alongside domain inhibitors for dissecting the mechanism by which these factors coordinate enhancer activity in normal and diseased cells.

dCBP-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

dCBP-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 46)Lieferanten
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Nantong HI-FUTURE Biology Co., Ltd.
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Hubei Chuchang Biotech Co., Ltd.
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ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795
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TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
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InvivoChem 		+1-708-310-1919 +1-13798911105
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Aladdin Scientific 		+1-+1(833)-552-7181
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Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
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Shanghai SuperLan Chemcial Technique Centre 021-2022843681 15618226720
 lucy@atkchemical.com China 9952 58
  • 5H-Pyrazolo[4,3-c]pyridine-5-carboxamide, 3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1-[1-[15-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-5-yl]amino]-1-oxo-4,7,10,13-tetraoxapentadec-1-yl]-4-piperidinyl]-1,4,6,7-tetrahydro-N-methyl-
  • dCBP-1
  • 3-(7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(1-(1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-5-yl)amino)-3,6,9,12-tetraoxapentadecan-15-oyl)piperidin-4-yl)-N-methyl-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide
  • Inhibitor,p300,multiple,CRBN,myeloma,cell,degrader,PROTACs,MYC,CBP,inhibit,dCBP 1,dCBP1,heterobifunctional,Epigenetic Reader Domain,dCBP-1
  • 2484739-25-3
  • C51H63F2N11O10
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