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Pomalidomide-6-2-2-6-N3

Pomalidomide-6-2-2-6-N3 Struktur
2300178-66-7
CAS-Nr.
2300178-66-7
Englisch Name:
Pomalidomide-6-2-2-6-N3
Synonyma:
Poma-6-2-2-6-N3;Pomalidomide-6-2-2-6-N3;Pomalidomid-C6-PEG3-butyl-N3;Pomalidomide-C?-PEG?-butyl azide;Pomalidomide-C6-PEG3-butyl azide;Hexanamide, 6-[2-[2-[(6-azidohexyl)oxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
CBNumber:
CB28363888
Summenformel:
C29H40N6O8
Molgewicht:
600.67
MOL-Datei:
2300178-66-7.mol

Pomalidomide-6-2-2-6-N3 Eigenschaften

storage temp. 
2-8°C
Aggregatzustand
powder or crystals

Sicherheit

Pomalidomide-6-2-2-6-N3 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Protein degrader builiding block Pomalidomide-C6-PEG3-Butyl Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-6-2-2-6-N3 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Pomalidomide-6-2-2-6-N3 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 12)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alfa Chemistry

Info@alfa-chemistry.com United States 24072 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068
1924344760@confluore.cn China 2996 58
Aladdin Scientific

tp@aladdinsci.com United States 52924 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068
1924344760@qq.com China 4825 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624
1927928688@qq.com China 1474 58
Zhengzhou convergence chemical co., LTD 0371-0371-55153829 18003835034
2853979819@qq.com China 9857 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822
czbjpharma@126.com China 18478 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 13417589054
trendseenbio@gmail.com China 9070 58
Xi‘a(chǎn)n Deeptech Biotechnology Co.,LTD +86-15114901355 +86-15114901355
15114901355@163.com China 190 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 176345344 7 17634854698
1959525201@qq.com China 8066 58

  • Pomalidomide-6-2-2-6-N3
  • Poma-6-2-2-6-N3
  • Pomalidomide-C?-PEG?-butyl azide
  • Pomalidomid-C6-PEG3-butyl-N3
  • Hexanamide, 6-[2-[2-[(6-azidohexyl)oxy]ethoxy]ethoxy]-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
  • Pomalidomide-C6-PEG3-butyl azide
  • 2300178-66-7
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