LAMININ
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- CAS-Nr.
- 114956-81-9
- Englisch Name:
- LAMININ
- Synonyma:
- LAMININ;laminin, LN;LN, Human laminin;LAMININ, HUMAN PLACENTA;laminin from human placenta;Laminin from human fibroblasts
;cell culture derived, liquid, sterile-filtered;LAMININ FROM HUMAN PLACENTA CELL*CULTURE TESTED;laminin from engelbreth-holm-swarm murine sarcoma basement membrane;Laminin β2 (mouse clone λ573/λ281/p57/λ34/λ6 protein moiety reduced)
- CBNumber:
- CB2711739
- Summenformel:
- NULL
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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LAMININ Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- liquid
- Farbe
- Colorless to light yellow
- Biologische Quelle
- mouse (Engelbreth-Holm-Swarm mouse sarcoma basement membrane)
LAMININ Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Laminin from human fibroblasts has been used:
- in coating six-well plates for wound healing assay
- as a substrate in cell adhesion and spreading assay
- for differentiation of human embryonic stem cells (hESCs) and human induced pluripotent stem cells (hiPSCs) toward dopaminergic neurons
- in corneal endothelial cell wound healing (migration) assay and corneal endothelial cell barrier assay
Laminin from human fibroblasts is recommended for use as a cell culture substratum at 1-2 μg/cm
2. The optimal concentration does depend on cell type as well as the application or research objectives.
Allgemeine Beschreibung
Laminin is purified as laminin-nidogen complex from mouse Engelbreth-Holm-Swarm (EHS) sarcoma. Laminin is a heterotrimer made from α, β and γ chain subunits. It is a glycoprotein which is required for the structural scaffolding of basement membranes. Laminin supports growth and differentiation of many cell types including epithelial, endothelial, neural, muscle and liver cells.
Biological activity: Tested for the promotion of adherence of HT-1080 cells.
Species specificity: Active on most mammalian cells.
Biochem/physiol Actions
Laminin proteins are integral components of structural scaffolding in animal tissues. They associate with type IV collagen via entactin and perlecan and bind to cell membranes through integrin receptors, dystroglycan glycoprotein complexes and Lutheran blood group glycoproteins. Laminin has active domains for collagen binding, cell adhesion, heparin binding, and neurite outgrowth fragment.
LAMININ Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
LAMININ Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 63)Lieferanten
114956-81-9()Verwandte Suche:
Dichloro(ethylendiamin)platin
(Ethylenbis(nitrilomethylidyn)-2,2'-diphenolato)cobalt(II)
1,1,3,3-Tetramethylbutylisocyanat
Kupfer(II)-4-oxopent-2-en-2-olat
Phenylselenol
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')europium
Benzylisocyanid
Tris(2,2,6,6-tetramethylheptan-3,5-dionato-O,O')dysprosium
(p-Toluolsulfonyl)methylisocyanid
Methylisocyanacetat
Aluminiumtris(2,4-pentandionato-O,O')
(Pentan-2,4-dionato-O,O')silber
N-Butylisocyanid
Ethylisocyanacetat
Tris(pentan-2,4-dionato)eisen(II)
2-Methylpropylisocyanid
- LAMININ FROM HUMAN PLACENTA CELL*CULTURE TESTED
- LAMININ
- LAMININ, HUMAN PLACENTA
- LAMININ FROM BASEMENT MEMBRANE OF ENGELBRETH HOLM-SWARM TRANSPLANTABLE MOUSE TUMOR
- laminin from engelbreth-holm-swarm murine sarcoma basement membrane
- laminin from human placenta
- Laminin from human fibroblasts
- LN, Human laminin
- laminin, LN
- cell culture derived, liquid, sterile-filtered
- Laminin from Engelbreth-Holm-Swarm murine sarcoma basement membrane 1-2 mg/mL in Tris buffered NaCl, 0.2 mum filtered, BioReagent, suitable for cell culture
- Laminin β2 (mouse clone λ573/λ281/p57/λ34/λ6 protein moiety reduced)
- 114956-81-9
- Cell Signaling and Neuroscience
- Cell Biology
- BioChemical
- Extracellular Matrix
- Extracellular Matrix Peptides and Proteins
- Cytoskeleton and Extracellular Matrix
