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Flubendazol

Flubendazole Struktur
31430-15-6
CAS-Nr.
31430-15-6
Bezeichnung:
Flubendazol
Englisch Name:
Flubendazole
Synonyma:
FLUBENDAZOL;Flubendazole Polymorph B;R-17899;R 17889;FLUMOXAL;FLUBENOL;FLUVERNAL;FLUMOXANE;fluvermal;Flubenvet
CBNumber:
CB2669630
Summenformel:
C16H12FN3O3
Molgewicht:
313.28
MOL-Datei:
31430-15-6.mol

Flubendazol Eigenschaften

Schmelzpunkt:
290°C
Dichte
1.3720 (estimate)
storage temp. 
2-8°C
L?slichkeit
Practically insoluble in water, in alcohol and in methylene chloride
pka
10.66±0.10(Predicted)
Aggregatzustand
Solid
Farbe
White to Off-White
Merck 
14,4118
CAS Datenbank
31430-15-6(CAS DataBase Reference)
Sicherheit
  • Risiko- und Sicherheitserkl?rung
  • Gefahreninformationscode (GHS)
R-S?tze: 22
S-S?tze: 44
WGK Germany  2
RTECS-Nr. DD6497500
HS Code  29339900
Toxizit?t LD50 in mice, rats, guinea pigs (mg/kg): >2560 orally (Thienpont)
Bildanzeige (GHS) GHS hazard pictograms
Alarmwort Warnung
Gefahrenhinweise
Code Gefahrenhinweise Gefahrenklasse Abteilung Alarmwort Symbol P-Code
H361 Kann vermutlich die Fruchtbarkeit beeintr?chtigen oder das Kind im Mutterleib sch?digen. Reproduktionstoxizit?t Kategorie 2 Warnung P201, P202, P281, P308+P313, P405,P501
Sicherheit
P201 Vor Gebrauch besondere Anweisungen einholen.
P202 Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.
P281 Vorgeschriebene pers?nliche Schutzausrüstung verwenden.
P308+P313 BEI Exposition oder falls betroffen: ?rztlichen Rat einholen/?rztliche Hilfe hinzuziehen.
P405 Unter Verschluss aufbewahren.
P501 Inhalt/Beh?lter ... (Entsorgungsvorschriften vom Hersteller anzugeben) zuführen.

Flubendazol Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Flubendazole is a benzimidazole carbamate anthelmintic. It completely eliminates larvae in a mouse model of A. cantonensis infection and exhibits a mean larval reduction of 100% in a T. spiralis infection model when administered at doses of 5 and 50 mg/kg per day, respectively. Flubendazole inhibits mammalian tubulin polymerization (IC50 = 2.5 μM) and inhibits binding of [3H]mebendazole to H. contortus L3 larval tubulin (IC50 = 0.17 μM). Flubendazole also inhibits the proliferation of BT-549, SK-BR-3, MDA-MB-231, and MCF-7 breast cancer cells (IC50s = 0.72, 1.51, 1.75, and 5.51 μM, respectively) and reduces tumor growth in an MDA-MB-231 mouse xenograft model when administered at a dose of 25 mg/kg.

Chemische Eigenschaften

White Solid

Verwenden

An anthelmintic.

Definition

ChEBI: A member of the class of mebendazole in which the benzoyl group is replaced by a p-fluorobenzoyl group. A broad-spectrum anthelmintic, it is used, particularly in veterinary medicine, for the treatment of nematodal infections.

Allgemeine Beschreibung

Flubendazol is a broad spectrum anthelmintic, which belongs to the class of compounds known as benzimidazoles. It can be widely used in veterinary and human medicine. It mainly finds applications in deworming poultry, swine, dogs and cats.

Flubendazol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Flubendazol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 416)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hebei Chuanghai Biotechnology Co., Ltd
+86-15531157085 +86-15531157085
abby@chuanghaibio.com China 8805 58
Hebei Mujin Biotechnology Co.,Ltd
+86 13288715578 +8613288715578
sales@hbmojin.com China 12824 58
Hebei Chuanghai Biotechnology Co,.LTD
+86-13131129325
sales1@chuanghaibio.com China 5878 58
Changzhou Rokechem Technology Co., Ltd.
18758118018
sales001@rokechem.com China 255 58
Hebei Chuanghai Biotechnology Co., Ltd
+8615531151365
mina@chuanghaibio.com China 18141 58
airuikechemical co., ltd.
+86-18353166132 +86-18353166132
sales02@airuikechemical.com China 983 58
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
+86-13572219112 +86-15029287646
info@pushanshiye.com China 165 58
Hebei Zhuanglai Chemical Trading Co Ltd
+86-16264648883 +86-16264648883
niki@zlchemi.com China 3712 58
Hebei Junhua Import and Export Co., LTD
+86-18503288844 +86-18503288844
junhua1@hb-junhua.com China 1000 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21631 55

31430-15-6(Flubendazol)Verwandte Suche:


  • METHYL [5-(4-FLUOROBENZOYL)-1H-BENZIMIDAZOL-2-YL]CARBAMATE
  • CARBAMIC ACID, [5-(4-FLUOROBENZOYL)-1H-BENZIMIDAZOL-2-YL]-METHYL ESTER
  • FLUMOXAL
  • FLUMOXANAL
  • FLUMOXANE
  • FLUBENDAZOLE
  • FLUBENOL
  • FLUVERNAL
  • [5-(4-FLUOROBENZOYL)-1H-BENZIMIDAZOL-2-YL]CARBAMIC ACID, METHYL ESTER
  • (5-(4-fluorobenzoyl)-1h-benzimidazol-2-yl)-carbamicacimethylester
  • (5-(4-fluorobenzoyl)-1h-benzimidazole-2-yl)carbamicacidmethylester
  • [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamic Acid Methyl Ester Methyl [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamate
  • Flubendazole (FlutelMiuM)
  • flubendazole Solution, 100ppm
  • Flubendazole Imp. (EP)
  • Flubendazol, >=99%
  • [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamic Acid Methyl Ester
  • Methyl [5-(4-Fluorobenzoyl)benzimidazol-2-yl]carbamate
  • 5-(p-fluorobenzoyl)-2-benzimidazolecarbamicacimethylester
  • fluvermal
  • methyln-(5-(p-fluorobenzoyl)-2-benzimidazolyl)carbamate
  • 5-(p-fluorobenzoyl)-2-benzimidazolecarbamic acid methyl este
  • [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-,methyl ester
  • Flumoxanal, Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate
  • 5-(p-Fluorobenzoyl)-1H-benzimidazole-2-carbamic acid methyl ester
  • R-17899
  • 5-(p-Fluorobenzoyl)-2-benzimidazolecarbamic acid, Methyl ester
  • flubendazole standard
  • Methyl (5-(4-fluorobenzoyl)-1H-benzo[d]iMidazol-2-yl)carbaMate
  • Flubenvet
  • Methyl (5-p-Fluorobenzoyl-2-benziMidazolyl)carbaMate
  • N-[6-(4-Fluorobenzoyl)-1H-benziMidazol-2-yl]carbaMic Acid Methyl Ester
  • NSC 313680
  • R 17889
  • Flubendazole PolyMorph B COS
  • N-[6-[(4-fluorophenyl)-oxomethyl]-1H-benzimidazol-2-yl]carbamic acid methyl ester
  • Flubendazole for system suitability CRS
  • Flubendazole CRS
  • Flubendazole>
  • ubendazoL
  • Carbamic acid, N-[6-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]-, methyl ester
  • Flubendazole Solution in DMSO, 1000μg/mL
  • Flubendazole USP/EP/BP
  • FLUBENDAZOL
  • Flubendazole Polymorph B
  • Flubendazole EP
  • Flumoxanal|||Flumoxane|||NSC 313680|||Fluvermal
  • Flubendazole in methanol
  • Flubendazole in DMSO
  • Flubendazole 100 μg/ml Acetonitrile
  • C13678000 Flubendazole
  • Flubendazole in Acetonitrile:DMF=1:1
  • Flubendazole, 10 mM in DMSO
  • Fluorophenyl Imidazole
  • 31430-15-6
  • C16H12FN3O3
  • C16H12N3O3F
  • Fluorobenzene
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