TAU-441 HUMAN Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Tau-441 human has been used to study its effects on mitochondrial transport velocities found in glial cells.
Allgemeine Beschreibung
Tau-441 human, recombinant, is an isoform of Tau, variant 2N4R, having 4 microtubule binding repeats (R) and 2 amino terminal inserts (N). Tau is a family of neuronal microtubule-associated proteins. Tau, a phosphoprotein is considered as an important microtubule associated protein (MAP) of a mature neuron. The 2N4R tau consists of 441 amino acids (tau441) and is considered as the largest size human brain tau. In human brain, tau is present in six molecular isoforms.
Biochem/physiol Actions
Microtubule associated protein tau (MAPT) plays an important role in the assembly and maintenance of the microtubule structure. Loss of expression of MAPT results in developmental delay and learning disability. The protein has been associated with pathology of Alzheimer′s disease (AD).
TAU-441 HUMAN Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
