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(+/-)-BAY K 8644

(+/-)-BAY K 8644 Struktur
93468-89-4
CAS-Nr.
93468-89-4
Englisch Name:
(+/-)-BAY K 8644
Synonyma:
BAY K-8644 (+/-);(+/-)-BAY K 8644;(±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem;(+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER;1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
CBNumber:
CB2471785
Summenformel:
C16H15F3N2O4
Molgewicht:
356.3
MOL-Datei:
93468-89-4.mol

(+/-)-BAY K 8644 Eigenschaften

Schmelzpunkt:
166-172 °C
storage temp. 
2-8°C
L?slichkeit
DMSO: 184 mg/mL
Aggregatzustand
Yellow solid

Sicherheit

Kennzeichnung gef?hrlicher Xi
R-S?tze: 36/38
S-S?tze: 26-36
WGK Germany  3

(+/-)-BAY K 8644 Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R36/38:Reizt die Augen und die Haut.

S-S?tze Betriebsanweisung:

S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Allgemeine Beschreibung

Synthetic dihydropyridine derivative that acts as an active Ca2+ slow channel agonist in neuroendocrine, muscle, thyroid and other cell types. Prolongs single channel open time without affecting the close time. An L-type Ca2+ channel agonist. Composed of two optical isomers. The (-)-enantiomer has strong vasoconstrictive, positive inotropic, and Ca2+ agonistic properties, whereas the (+)-enantiomer has weakly vasodilating, negative inotropic, and Ca2+ antagonistic properties. The net effect of the racemic mix is that of the negative enantiomer. Promotes β-cell proliferation/regeneration.

Biochem/physiol Actions

Primary TargetL-type Ca2+ channel

(+/-)-BAY K 8644 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

(+/-)-BAY K 8644 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2'-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID METHYL ESTER
  • 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-[2-(TRIFLUOROMETHYL)PHENYL]-3-PYRIDINECARBOXYLIC ACID, METHYL ESTER
  • 1,4-DIHYDRO-2,6-DIMETHYL-5-NITRO-4-(2-[TRIFLUOROMETHYL]PHENYL)PYRIDINE-3-CARBOXYLIC ACID METHYL ESTER
  • (+/-)-BAY K 8644
  • BAY K-8644 (+/-)
  • (+)-(S)-1,4-dihydro-2,6-dimethyl-3-nitro-4-(2-trifluoromethylphenyl)pyridine-5-carboxylic acid
  • (±)-Bay K 8644 - CAS 93468-89-4 - Calbiochem
  • 93468-89-4
  • BioChemical
  • Biochemicals and Reagents
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors by Type
  • Enzyme Inhibitors
  • Substrate Analogs
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