nalanthalide Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Nalanthalide is a diterpenoid pyrone fungal metabolite that has been found in Nalanthamala and has potassium channel inhibitory and antiviral activities. It inhibits binding of the potassium channel inhibitor charybdotoxin to Jurkat cell membranes (IC₅₀ = 3 μM) and inhibits rubidium efflux from CHO cells expressing the voltage-gated potassium (K_v) channel K_v1.3 (IC₅₀ = 3.9 μM). Nalanthalide depolarizes T cells in vitro with an EC₅₀ value of 500 nM. It also inhibits HIV-1 integrase activity with IC₅₀ values of 10 and 25 μM in coupled and strand transfer assays, respectively.

nalanthalide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

nalanthalide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11973	58
Guangzhou Yaoguang Technology Co., Ltd.	13020159086	yangjue@ygfuture.com	China	421	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	23256	58
Tanmo Quality Inspection Technology Co., Ltd.	4008-099-669	23419001name@qq.com	CHINA	6043	58
Cayman Chemical Company	800-364-9897	sales@caymanchem.com	China	6838	58
Biosynth Biological Technology (Suzhou) Co Ltd	51288865780	sales@biosynth.com	China	6051	58
Shenzhen Campbell Biotechnology Co., Ltd.	18028747627		CHINA	0	58

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• nalanthalide
• 4H-Pyran-4-one, 3-[[(1R,4aR,5S,6S,8aR)-6-(acetyloxy)decahydro-5,8a-dimethyl-2-methylene-5-(4-methyl-3-penten-1-yl)-1-naphthalenyl]methyl]-2-methoxy-5,6-dimethyl-
• 3-[[(1R,4aR,5S,6S,8aR)-6-(acetyloxy)decahydro-5,8a-dimethyl-2-methylene-5-(4-methyl-3-penten-1-yl)-1-naphthalenyl]methyl]-2-methoxy-5,6-dimethyl-4H-pyran-4-one
• 145603-76-5