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7-Dehydrocholesterol-25,26,26,26,27,27,27-d7

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Struktur
388622-58-0
CAS-Nr.
388622-58-0
Englisch Name:
7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
Synonyma:
7-dehydro Cholesterol-d7;2H7]-7-Dehydrocholesterol;(3β)-7-Dehydro Cholesterol-d7 (Major);(32)-7-Dehydro Cholesterol-d7 (Major);7-Dehydrocholesterol-25,26,26,26,27,27,27-d7;(3β)-7-Dehydro Cholesterol-d7 (See also D229462);Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-;Cholecalciferol EP Impurity B-d7 (3-beta-7-Dehydro Cholesterol-d7)
CBNumber:
CB23335585
Summenformel:
C27H44O
Molgewicht:
384.65
MOL-Datei:
388622-58-0.mol

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Eigenschaften

storage temp. 
-70°C
L?slichkeit
Soluble in methanol(warmed), slightly soluble in chloroform
Aggregatzustand
solid
Stabilit?t:
Light Sensitive

Sicherheit

WGK Germany  3

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

7-dehydrocholesterol-d7 has been used:
  • as an internal standard: to spike Chlamydomonas CC-125 lipid extract for mass spectroscopy analysis
  • in liquid chromatography–mass spectrometry (LC-MS) for cultured cells oxysterol analysis
  • to treat and label SRD-1 cell (chinese hamster ovary (CHO) mutant cell-line) for gas chromatography/mass spectrometry (GC/MS) analysis

Allgemeine Beschreibung

7-dehydrocholesterol (7-DHC) is a cholesterol precursor and is localized in basal epidermal keratinocytes. 7DHC on photolysis in the presence of ultraviolet light B generates previtamin D3. The enzyme 7-dehydrocholesterol reductase (DHCR7) catalyzes the reduction of C(7-8) double bond of 7-DHC to cholesterol. 7-dehydrocholesterol-d7 is a deuterated derivative of 7-dehydrocholesterol.

Biochem/physiol Actions

7-Dehydrocholesterol (7-DHC) is used as a precursor for microbial vitamin D3 production. Impairment of 7-dehydrocholesterol reductase (DHCR7) functionality leads to 7-DHC accumulation and is implicated in Smith-Lemli-Opitz syndrome (SLOS).

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

7-Dehydrocholesterol-25,26,26,26,27,27,27-d7 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 24)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Creative Enzymes 		1-516-855-7709
info@creative-enzymes.com United States 8748 58
Shanghai Saikerui Biotechnology Co. , Ltd. 021-58000709 15900491054
 info@scrbio.com China 10329 58
Sigma-Aldrich 021-61415566 800-8193336
 orderCN@merckgroup.com China 51456 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
Nanjing Haolv Biotechnology Co.,Ltd 025-84622273 17361806303
 3004208264@qq.com China 3021 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774
sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
 sales@chemegen.com China 11218 58
Qingdao Tenglong microwave technology co., LTD. 0532-83818797 18561885118
 market@tlwb.com.cn China 3944 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822
 czbjpharma@126.com China 18478 58
Reer Technology (Shanghai) Co., LTD 021-64400900 15800436310
 bessey@reertech.com China 4105 58
  • 7-Dehydrocholesterol-25,26,26,26,27,27,27-d7
  • (3β)-7-Dehydro Cholesterol-d7 (See also D229462)
  • (3β)-7-Dehydro Cholesterol-d7 (Major)
  • Cholesta-5,7-dien-25,26,26,26,27,27,27-d7-3-ol, (3b)-
  • 7-dehydro Cholesterol-d7
  • (32)-7-Dehydro Cholesterol-d7 (Major)
  • 2H7]-7-Dehydrocholesterol
  • Cholecalciferol EP Impurity B-d7 (3-beta-7-Dehydro Cholesterol-d7)
  • 388622-58-0
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