DBCO-PEG4-SE
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- CAS-Nr.
- 1427004-19-0
- Englisch Name:
- DBCO-PEG4-SE
- Synonyma:
- DBCO-PEG4-SE;DBCO-PEG4-NHS;DBCO-PEG4-SPA;DBCO-PEG4-NHS easer;DBCO-PEG4-NHS ester;DBCO-CONH-PEG4-NHS ester;DBCO-PEG4-succinimidyl ester;Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester;inhibit,Inhibitor,DBCO PEG4 NHS ester,DBCOPEG4NHS ester,DBCO-PEG-4-NHS ester,PROTAC Linkers;2,5-Dioxo-1-pyrrolidinyl 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoate
- CBNumber:
- CB22984375
- Summenformel:
- C34H39N3O10
- Molgewicht:
- 649.69
- MOL-Datei:
- 1427004-19-0.mol
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DBCO-PEG4-SE Eigenschaften
- Dichte
- 1.33±0.1 g/cm3(Predicted)
- storage temp.
- -20°C
- L?slichkeit
- Soluble in DMSO, DCM, DMF
- pka
- 15.14±0.46(Predicted)
- Aggregatzustand
- gel or oil
- Farbe
- Colourless to yellow
- InChIKey
- RRCXYKNJTKJNTD-UHFFFAOYSA-N
- SMILES
- C(ON1C(=O)CCC1=O)(=O)CCOCCOCCOCCOCCNC(=O)CCC(N1CC2=CC=CC=C2C#CC2=CC=CC=C12)=O
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
| WGK Germany |
3 |
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| HS Code |
2942000090 |
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| Bildanzeige (GHS) |
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| Alarmwort |
Warnung |
| Gefahrenhinweise |
| Code |
Gefahrenhinweise |
Gefahrenklasse |
Abteilung |
Alarmwort |
Symbol |
P-Code |
| H302 |
Gesundheitssch?dlich bei Verschlucken. |
Akute Toxizit?t oral |
Kategorie 4 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P270, P301+P312, P330, P501 |
| H315 |
Verursacht Hautreizungen. |
Hautreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P302+P352, P321,P332+P313, P362 |
| H319 |
Verursacht schwere Augenreizung. |
Schwere Augenreizung |
Kategorie 2 |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
P264, P280, P305+P351+P338,P337+P313P |
| H335 |
Kann die Atemwege reizen. |
Spezifische Zielorgan-Toxizit?t (einmalige Exposition) |
Kategorie 3 (Atemwegsreizung) |
Warnung |
![GHS hazard pictograms]() src="/GHS07.jpg" width="20" height="20" /> |
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| Sicherheit |
| P261 |
Einatmen von Staub vermeiden. |
| P305+P351+P338 |
BEI KONTAKT MIT DEN AUGEN: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach M?glichkeit entfernen. Weiter spülen. |
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DBCO-PEG4-SE Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Succinimidyl ester (NHS, amine reactive) functionalized cyclooctyne derivative for incorporation of the cyclooctyne moiety into amine containing compounds or biomolecules. Cyclooctynes are useful in strain-promoted copper-free click chemistry cycloaddition reactions. This dibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.
Applications Include:
- Protein-peptide conjugates
- Antibody-enzyme or antibody-drug conjugates
- Protein or peptide-oligonucleotide conjugates
- Surface modification
DBCO-PEG4-SE Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
DBCO-PEG4-SE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 83)Lieferanten
- DBCO-PEG4-NHS ester
- DBCO-PEG4-SE
- DBCO-PEG4-succinimidyl ester
- Dibenzocyclooctyne-PEG4-N-hydroxysuccinimidyl ester
- DBCO-CONH-PEG4-NHS ester
- 2,5-Dioxo-1-pyrrolidinyl 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-4,7,10,13-tetraoxa-16-azaeicosanoate
- 4,7,10,13-Tetraoxa-16-azaeicosanoic acid, 20-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,20-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester
- DBCO-PEG4-SPA
- DBCO-PEG4-NHS
- inhibit,Inhibitor,DBCO PEG4 NHS ester,DBCOPEG4NHS ester,DBCO-PEG-4-NHS ester,PROTAC Linkers
- DBCO-PEG4-NHS easer
- 1427004-19-0
- peg
- ADC-Linkers
