天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione

(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione Struktur
92395-41-0
CAS-Nr.
92395-41-0
Englisch Name:
(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione
Synonyma:
Amrubicin intermediate;Amrubicin Intermediate 5;Amrubicinhydrochloride int5;9α-amino-9β-acetyl-7,8,9,10-tetrahydro-6,7α,11-trihydroxy-5,12-naphthacenedione;(7S,9S)-9-Acetyl-9-amino-6,7,11-trihydroxy-7,8,9,10-tetrahydro-5,12-tetracenedione;(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione;5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S)-
CBNumber:
CB22717140
Summenformel:
C20H17NO6
Molgewicht:
367.35
MOL-Datei:
92395-41-0.mol

(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione Eigenschaften

Schmelzpunkt:
158-159℃
Siedepunkt:
604.6±55.0 °C(Predicted)
Dichte
1.550±0.06 g/cm3(Predicted)
pka
7.92±0.60(Predicted)

Sicherheit

HS Code  2922500090

(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione can be used as organic synthesis intermediates and pharmaceutical intermediates. It is an intermediate in the synthesis of amrubicin. amrubicin is a third-generation synthetic anthracycline currently in development for the treatment of small cell lung cancer.

Synthese

Synthesis_92395-41-0
A mixture of R-9-acetamido-9- [1,1- (2,2-dimethylpropanedioxy) ethyl] -4,5-dihydro-6,13-dihydroxy -4,14- Methyl-14H-anthraceno [3,2-f] - [1,3] oxazolene-7,12-dione (Compound 4, R = CH3), 1200 g of 3N sulfuric acid aqueous solution and incubated at 60-70 ?? C for 8 hours. The pH of the solution was adjusted to 7-8 with aqueous sodium hydrogencarbonate solution, The combined chloroform layers were washed with water, dried, filtered and concentrated. The residue was stirred with isopropyl ether to give (+) - 9-amino-4-demethoxy-9-deoxo daunomycinone.

(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione Upstream-Materialien And Downstream Produkte

Upstream-Materialien

3,4-Dihydro-5,8-dimethoxynaphthalin-2(1H)-on

Downstream Produkte

(7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 14)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Speranza Chemical Co., Ltd. 		+86-86-075521030354 +8618688942810
 sophieliu@speranzachem.com China 802 55
Sense Chemicals (Shanghai) Co., Ltd. 		+86-21-52751036; +8613818977689
 david.dai@sensechemicals.com China 225 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418684 +8618949823763
 sales@tnjchem.com China 25356 58
Hebei Weibang Biotechnology Co., Ltd 		+8617732866630
 bess@weibangbio.com China 18150 58
Zibo Hangyu Biotechnology Development Co., Ltd 		+86-0533-2185556 +8617865335152
 Mandy@hangyubiotech.com China 10986 58
Wuhan EEChem Technologies Co., Ltd 0711-3617768 13308685235
 lihongcai4360@sina.com China 1383 55
Abydos Scientific 025-84767922 18936879710
 sales@abydoscientific.com China 1009 58
Speranza Chemical Co., Ltd. 0755-21030354 18126410231
 sales@speranzachem.com China 511 58
Changzhou Bojia Biomedical Technology Co., Ltd. 2122619822
 czbjpharma@126.com China 18478 58
WEITIXIHAUGONG 0371-53370800 18037197114
 2853031799@qq.com China 9998 58
  • (7S,9S)-9-Acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-5,12-naphthacenedione
  • Amrubicinhydrochloride int5
  • 5,12-Naphthacenedione, 9-acetyl-9-amino-7,8,9,10-tetrahydro-6,7,11-trihydroxy-, (7S,9S)-
  • 9α-amino-9β-acetyl-7,8,9,10-tetrahydro-6,7α,11-trihydroxy-5,12-naphthacenedione
  • Amrubicin intermediate
  • Amrubicin Intermediate 5
  • (7S,9S)-9-Acetyl-9-amino-6,7,11-trihydroxy-7,8,9,10-tetrahydro-5,12-tetracenedione
  • 92395-41-0
Copyright 2019 ? ChemicalBook. All rights reserved