BIBF 1202 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
BIBF 1202 is an active metabolite of the VEGFR, FGFR, and PDGFR inhibitor BIBF 1120 (nintedanib; ). It is formed from BIBF 1120 by intracellular esterases. BIBF 1202 inhibits VEGFR2 with an IC
50 value of 62 nM.
Verwenden
Nintedanib Carboxylic Acid is a related compound of Intedanib (I666650), an indolinone derivative that inhibits angiokinase and an antitumor agent.
BIBF 1202 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte