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Histone H3 (human recombinant)

Histone H3 (human recombinant) Struktur
CAS-Nr.
Englisch Name:
Histone H3 (human recombinant)
Synonyma:
Histone H3 (human recombinant)
CBNumber:
CB22591265
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

Histone H3 (human recombinant) Eigenschaften

Sicherheit

Histone H3 (human recombinant) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Histone H3 is a nuclear protein and a component of the nucleosome core, a basic unit of chromatin, that is essential for organizing genomic DNA in eukaryotic nuclei. It is a globular protein that contains an unstructured N-terminal tail that extends outside of the nucleosome core and is subject to various post-translational modifications (PTMs), including methylation, phosphorylation, acetylation, and citrullination. Histone H3 PTMs function as epigenetic regulators of gene transcription by affecting chromatin structure and providing binding sites for many transcription factors, thus regulating several cellular functions including gene expression, cell cycle, and DNA replication and repair. Differential methylation of histone H3 at various lysine residues is catalyzed by SET domain-containing methyltransferases and marks sites of transcriptional activation or repression. Citrullination of histone H3 by protein arginine deiminase 4 (PAD4; Item Nos. 10500 | 25915 | 28910) or PAD2 induces the release of neutrophil extracellular traps (NETs), a network of decondensed DNA and intracellular proteins secreted by neutrophils as a pathogen defense mechanism. Histone H3 mutations have been found in patients with diffuse intrinsic pontine glioma, leukemia, or chondroblastoma.

Histone H3 (human recombinant) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Histone H3 (human recombinant) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 11)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11218 58
Shanghai Universal Biotech Co.,Ltd 13774214275
zhouzz@univ-bio.com China 24994 58

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