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N-De[2-(Methylsulfonyl)ethyl] Lapatinib

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Struktur
697299-82-4
CAS-Nr.
697299-82-4
Englisch Name:
N-De[2-(Methylsulfonyl)ethyl] Lapatinib
Synonyma:
Lapatinib impurity O;Lapatinib Desmesylethyl Imp;Lapatinib Desmesylethyl Impurity;N-De[2-(methylsulfonyl)ethyl] Lapatinib;[6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]aMine;6-5-(Aminomethyl)furan-2-yl-N-3-chloro-4-(3-fluorophenyl)methoxyphenylquinazolin-4-amine;6-(5-(aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine;6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine;4-Quinazolinamine, 6-[5-(aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-
CBNumber:
CB22557856
Summenformel:
C26H20ClFN4O2
Molgewicht:
474.91
MOL-Datei:
697299-82-4.mol

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Eigenschaften

Schmelzpunkt:
>141oC (dec.)
Siedepunkt:
626.4±55.0 °C(Predicted)
Dichte
1.376±0.06 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
L?slichkeit
DMSO (Slightly), Methanol (Slightly, Heated)
pka
8.83±0.29(Predicted)
Aggregatzustand
Solid
Farbe
Pale Yellow to Light Beige

Sicherheit

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

A reactive metabolite of Lapatinib (L175800) which is associated with various drug toxicities. Lapatinib is metabolized mainly by P450 3A4 to form O- and N-dealkylated metabolites.

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-De[2-(Methylsulfonyl)ethyl] Lapatinib Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • [6-(5-AMinoMethylfuran-2-yl)quinazolin-4-yl][3-chloro- 4-(3-fluorobenzyloxy)phenyl]aMine
  • 6-[5-(AMinoMethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)Methoxy]phenyl]-4-quinazolinaMine
  • Lapatinib Desmesylethyl Imp
  • Lapatinib impurity O
  • 4-Quinazolinamine, 6-[5-(aminomethyl)-2-furanyl]-N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-
  • Lapatinib Desmesylethyl Impurity
  • 6-(5-(aminomethyl)furan-2-yl)-N-(3-chloro-4-((3-fluorobenzyl)oxy)phenyl)quinazolin-4-amine
  • 6-5-(Aminomethyl)furan-2-yl-N-3-chloro-4-(3-fluorophenyl)methoxyphenylquinazolin-4-amine
  • N-De[2-(methylsulfonyl)ethyl] Lapatinib
  • 697299-82-4
  • C26H20ClFN4O2
  • Aromatics
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Metabolites & Impurities
  • Pharmaceuticals
  • Sulfur & Selenium Compounds
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