天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

ACOLBIFENE

ACOLBIFENE Struktur
151533-34-5
CAS-Nr.
151533-34-5
Englisch Name:
ACOLBIFENE
Synonyma:
ACOLBIFENE;(Rac)-EM-652;rac-Acolbifene;2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-;2-[4-[2-(1-piperidino)ethoxy]phenyl]-3-(4-hydroxyphenyl)-4-Methyl-7-hydroxy-2H-1-benzopyran
CBNumber:
CB22451259
Summenformel:
C29H31NO4
Molgewicht:
457.56
MOL-Datei:
151533-34-5.mol

ACOLBIFENE Eigenschaften

Siedepunkt:
651.5±55.0 °C(Predicted)
Dichte
1.217±0.06 g/cm3(Predicted)
L?slichkeit
DMSO: 100 mg/mL (218.55 mM)
pka
9.70±0.40(Predicted)
Aggregatzustand
Crystal
Farbe
Purple to purplish red

Sicherheit

ACOLBIFENE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

The prodrug EM-800 is an orally active nonsteroidal anties trogen and is a triphenylethylene rigid analogue. EM-800 undergoes ester hydrolysis to the active m etabolite acolbifene. This fourth-generation antiestrogen is 200-fold more potent than tam oxifen in breast and uterine cancer cells and is effective in patients for whom tamoxifen therapy has failed. The mechanistic rationale for the effectiveness of acolbifene in tamoxifen-resistant tumors is based on the fact that it inhibits both the AF-1 and AF-2 activation pathways and does not poss ess any intrinsic estrogenic action. Acolbifene enjoys a 60% breast cancer cure rate. Structurally, acolbifene resembles raloxifene, with a benzopyran ring substituted for the benz othiophene ring. An additional benefit observed with acolbifene is its protective effect on bone loss. Adverse effects include nausea and vomiting.

ACOLBIFENE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


ACOLBIFENE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 24)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 96815 76
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
China 1493 55
LETOPHARM LIMITED +86-21-5821 5861
sales@letopharm.com China 2384 58
SPIRO PHARMA
eric_feng1954@126.com China 9248 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
info@efebio.com China 9806 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 +86-13028896684;
sales@rrkchem.com China 57423 58
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44806 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223;
psaitong@jm-bio.com China 29774 58

  • 2-[4-[2-(1-piperidino)ethoxy]phenyl]-3-(4-hydroxyphenyl)-4-Methyl-7-hydroxy-2H-1-benzopyran
  • rac-Acolbifene
  • ACOLBIFENE
  • (Rac)-EM-652
  • 2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-
  • 151533-34-5
Copyright 2019 ? ChemicalBook. All rights reserved