Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast
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- CAS-Nr.
- Englisch Name:
- Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast
- Synonyma:
- gspt1;zgc:91975;Anti-GST1;Anti-GTH4;Anti-ETF3A;Anti-eRF3a;Anti-GSTM2;Anti-GST1, homolog of yeast;GTP-binding protein GST1-HS;Anti-G1 to S phase transition 1
- CBNumber:
- CB22100689
- Summenformel:
- Molgewicht:
- 0
- MOL-Datei:
- Mol file
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Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Eigenschaften
- storage temp.
- -20°C
- Aggregatzustand
- buffered aqueous solution
Sicherheit
- Risiko- und Sicherheitserkl?rung
- Gefahreninformationscode (GHS)
Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Anti-eRF3a/GSPT1 (N-terminal) antibody produced in rabbit is suitable for immunoprecipitation at a concentration of 2-5μL using HeLa cell lysates and western blotting at a dilution of 1:500-1:1,000 using HeLa cell lysates.
Allgemeine Beschreibung
Eukaryotic release factor 3 a (eRF3a) is encoded by the gene G1 to S phase transition 1 (GSPT1) in humans. The eRF3a/GSPT1 exon 1 is a translation termination protein characterized with a tri-nucleotide GGC repeat coding for a polyglycine expansion in the amino-terminal end.
Biochem/physiol Actions
Eukaryotic release factor 3a (eRF3a) is a translation termination protein that is encoded by G1 to S phase transition 1 gene (GSPT1) in humans. The eRF3a/GSPT1 exon 1 contains a tri-nucleotide GGC repeat coding for a polyglycine expansion in the N-terminal of the protein. It is associated with protein translation as a regulator of apoptosis signal-regulating kinase 1 (ASK1). GSPT1 interacts with ASK1 and enhances ASK1-induced apoptotic activity by activating caspase-3. It plays a novel role in the regulation of ASK1-mediated apoptosis. GSPT1 is found to be up-regulated in various human cancers and is considered as a potential proto-oncogene.
Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 3)Lieferanten
- Anti-eRF3a/GSPT1 (N-terminal) antibody produced in rabbit
- Anti-Eukaryotic Release Factor 3a, Anti-G1 to S phase transition 1, Anti-GST1, homolog of yeast
- Anti-eRF3a/GSPT1 antibody produced in rabbit
- Anti-eRF3a
- Anti-ETF3A
- Anti-GSPT1 antibody produced in rabbit
- Anti-GST1
- gspt1
- zgc:91975
- Anti-Eukaryotic Release Factor 3a
- Anti-G1 to S phase transition 1
- Anti-GST1, homolog of yeast
- G1 to S phase transition protein 1 homolog
- GTP-binding protein GST1-HS
- Anti-GSTM1/GSTM2 antibody produced in goat
- Anti-GSTM2
- Anti-GTH4
