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Suxibuzon

4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER] Struktur
27470-51-5
CAS-Nr.
27470-51-5
Bezeichnung:
Suxibuzon
Englisch Name:
4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]
Synonyma:
ae-17;flogos;alfide;solurol;Aflogan;Calibene;SUXIBUZONE;Suxibuzona;lidinedione;Suxibuzonum
CBNumber:
CB2196749
Summenformel:
C24H26N2O6
Molgewicht:
438.47
MOL-Datei:
27470-51-5.mol

Suxibuzon Eigenschaften

Schmelzpunkt:
126-127°
Siedepunkt:
550.33°C (rough estimate)
Dichte
1.2847 (rough estimate)
Brechungsindex
1.6300 (estimate)
storage temp. 
2-8°C
L?slichkeit
Practically insoluble in water, freely soluble in acetone, soluble in ethanol (96 per cent), practically insoluble in cyclohexane.
Aggregatzustand
Solid
pka
4.33±0.17(Predicted)
Farbe
White to Off-White
CAS Datenbank
27470-51-5

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 20/21/22
S-S?tze: 36
WGK Germany  3
RTECS-Nr. WM9640000
Toxizit?t LD50 orally in mice: 5.683 micromol/kg (Esteve, 1973)

Suxibuzon Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.

S-S?tze Betriebsanweisung:

S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.

Chemische Eigenschaften

White or almost white, crystalline powder.

Verwenden

analgesic, antipyretic, antiinflammatory

Definition

ChEBI: A pyrazolidine that is phenylbutazone which is substituted by a 3-carboxypropanoylmethyl group at the 4-position. Suxibuzone is a prodrug for phenylbutazone and is commonly used as an anti-inflammatory drug in horses.

Weltgesundheitsorganisation (WHO)

Suxibuzone, a pyrazolone derivative with anti-inflammatory, analgesic and antipyretic activity, was introduced in 1974 for the treatment of rheumatic disorders. As it is structurally related to phenylbutazone, it is subjected to rigorously restricted indications by some national regulatory authorities. See WHO comment for phenylbutazone.

Suxibuzon Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Suxibuzon Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 89)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Nextpeptide Inc
+86-0571-81612335 +8613336028439
sales@nextpeptide.com China 19908 58
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896
cbc@coresyn.com China 9984 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD
+86-0512-83500002 +8615195660023
sales@senfeida.com China 23046 58
Aceschem Inc.
+1-817863-6948 +1-(817)863-6948
sales@aceschem.com United States 19632 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
LEAPCHEM CO., LTD.
+86-852-30606658
market18@leapchem.com China 43340 58
Shanghai Acmec Biochemical Technology Co., Ltd.
+undefined18621343501
product@acmec-e.com China 33338 58

27470-51-5(Suxibuzon)Verwandte Suche:


  • 4-BUTYL-4-[HYDROXYMETHYL]-1,2-DIPHENYL-3,5-PYRAZOLIDINEDIONE HYDROGEN SUCCINATE [ESTER]
  • 4-butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedio
  • 4-butyl-4-hydroxymethyl-1,2-diphenyl-3,5-pyrazolidinedionehydrogensuccinate
  • ae-17
  • alfide
  • SUXIBUZONE
  • butanedioicacid,mono((4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl
  • flogos
  • lidinedione
  • solurol
  • succinicacid,monoesterwith4-butyl-4-(hydroxymethyl)-1,2-diphenyl-3,5-pyrazo
  • 3-(1,2-Diphenyl-3,5-dioxo-4-butylpyrazolidine-4-ylmethoxycarbonyl)propionic acid
  • Succinic acid hydrogen (1,2-diphenyl-3,5-dioxo-4-butylpyrazolidin-4-yl)methyl ester
  • Succinic acid hydrogen (4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl ester
  • Succinic acid hydrogen 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester
  • 3-((4-Butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methoxycarbonyl)propionsaeure
  • 3,5-Pyrazolidinedione, 4-butyl-4-(hydroxymethyl)-1,2-diphenyl-, hydrogen succinate (ester)
  • 4-Butyl-4-(beta-carboxypropionyl-oxymethyl)-1,2-diphenyl-3,5-pyrazolidinedione
  • 4-Hydroxymethylbutazolidine hemisuccinate
  • Aflogan
  • Acetanilide Impurity 1
  • Suxibuzone CRS
  • Butanedioic acid, 1-[(4-butyl-3,5-dioxo-1,2-diphenyl-4-pyrazolidinyl)methyl] ester
  • 4-((4-butyl-3,5-dioxo-1,2-diphenylpyrazolidin-4-yl)methoxy)-4-oxobutanoic acid
  • Calibene
  • Suxibuzona
  • Suxibuzonum
  • Inhibitor,Suxibuzone,inhibit
  • 1-[3-[2-(dimethylamino)ethyl]-1-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfon amide
  • 27470-51-5
  • Biochemicals and Reagents
  • BioChemical
  • Substrate Analogs
  • Enzyme Inhibitors by Type
  • Enzymes, Inhibitors, and Substrates
  • Enzyme Inhibitors
  • DANILON
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