Polyinosinic-polycytidylic acid sodium salt
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- CAS-Nr.
- 42424-50-0
- Englisch Name:
- Polyinosinic-polycytidylic acid sodium salt
- Synonyma:
- Poly (I:C) Na;Poly(I:C) sodium;POLY I POLY C, NA;Polymyocyte sodium salt;POLY[I] POLY[C] SODIUM SALT;polyinosinic-polycytidylic acid sodium;polyI-polyC sodium salt compound solution;POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT;Polyinosinicacid-polycytidylicacidsodiumsal;POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT
- CBNumber:
- CB2187556
- Summenformel:
- C19H27N7O16P2
- Molgewicht:
- 671.41
- MOL-Datei:
- 42424-50-0.mol
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Polyinosinic-polycytidylic acid sodium salt Eigenschaften
- storage temp.
- −20°C
- L?slichkeit
- H2O: soluble10mg/mL
- Aggregatzustand
- lyophilized powder
- Farbe
- White to off-white
- Biologische Quelle
- synthetic (organic)
- Wasserl?slichkeit
- Water : 10 mg/mL (Need ultrasonic and warming)
- InChIKey
- ACEVNMQDUCOKHT-WOQDZEJINA-N
- SMILES
- O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=CC(N)=NC1=O)O.O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O |&1:1,2,3,11,22,23,24,32,r|
Sicherheit
| S-S?tze: |
22-24/25 |
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| WGK Germany |
3 |
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| RTECS-Nr. |
TR0175000 |
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Polyinosinic-polycytidylic acid sodium salt Chemische Eigenschaften,Einsatz,Produktion Methoden
S-S?tze Betriebsanweisung:
S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
Verwenden
TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. Polyinosinic-polycytidylic acid sodium salt is a double-stranded homopolymer used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
Biologische Aktivit?t
Polyinosinic-polycytidylic acid sodium (Poly(I:C) sodium) is a synthetic analog of double-stranded RNA and an agonist of toll-like receptor 3 (TLR3) and retinoic acid inducible gene I (RIG-I)-like receptors (RIG-I and MDA5). Polyinosinic-polycytidylic acid sodium can be used as a vaccine adjuvant to enhance innate and adaptive immune responses, and to alter the tumor microenvironment. Polyinosinic-polycytidylic acid sodium can directly trigger cancer cells to undergo apoptosis.
Polyinosinic-polycytidylic acid sodium salt Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
Polyinosinic-polycytidylic acid sodium salt Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 128)Lieferanten
42424-50-0()Verwandte Suche:
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1,1,3,3-Tetramethylbutylisocyanat
- POLYINOSINIC ACID + POLYCYTIDYLIC ACID, SODIUM SALT
- POLYINOSINIC ACID POLYCYTIDYLIC ACID, SODIUM SALT
- POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT
- POLY I POLY C, NA
- POLY[I] POLY[C] SODIUM SALT
- Oligochitosan-kanamycin-polyI-polyC sodium salt compound solution
- Polyinosinic acid - polycytidylic acid sodium salt, double-stranded
- Polyinosinic Acid . Polycytidylic Acid, Sodium Salt, Double
- polyinosinic-polycytidylic acid sodium
- Polymyocyte sodium salt
- Polyinosinic–polycytidylic Acid Sodium Salt（Poly I:C ）
- polyI-polyC sodium salt compound solution
- Poly(I:C) sodium
- POLYINOSINIC-POLYCYTIDYLIC ACID SODIUM SALT USP/EP/BP
- Polyi polycytidylic acid sodium salt(Poly I:C) (PIC)
- Poly (I:C) Na
- Polyinosinicacid-polycytidylicacidsodiumsal
- Polyinosinic-polycytidylic acid sodium salt gamma-irradiated
- 42424-50-0
- BioChemical
- Biochemicals and Reagents
- Synthetic Oligonucleotides and Related Reagents
- Nucleosides, Nucleotides, Oligonucleotides
- Biochemicals and Reagents
- Biomaterials
- Cell Culture
- Materials Science
- Nucleosides
- Nucleotides
- Oligonucleotide Polymers and Copolymers
- Oligonucleotides
- Other adjuvants
- Synthetic Oligonucleotides and Related Reagents
- Vaccine Adjuvants
- Vaccine Production
- Nucleoside Mono
