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CASPASE-1

CASPASE-1 Struktur
122191-40-6
CAS-Nr.
122191-40-6
Englisch Name:
CASPASE-1
Synonyma:
ICE;CASP-1;IL-1BC;CASPASE-1;ICE 1B HUMAN;P45) USP/EP/BP;CASPASE 1 HUMAN;IL-1 β converting enzyme;IL-1BETA CONVERTING ENZYME;Interleukin-1β-Converting Enzyme
CBNumber:
CB2155407
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

CASPASE-1 Eigenschaften

storage temp. 
−70°C

Sicherheit

WGK Germany  -

CASPASE-1 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Caspase 1 human has been used in in vitro cleavage assay with Rab interacting lysosomal protein (RILP) and in the cleavage of caspases-3/7 in human monocytic?cells (THP1).

Allgemeine Beschreibung

Caspase 1, also called interleukin (IL)-1-converting enzyme, is mapped to human 11q22.3. It belongs to the aspartate-specific cysteine proteases family and is primarily synthesized as procaspase-1 zymogen, which later become catalytically active post autoproteolysis. The enzymatically active caspase-1 comprises two p20/p10 heterodimer making it a tetramer.

Biochem/physiol Actions

Caspase 1 catalyzes the conversion of pro-inflammatory cytokine, pro-interleukin (IL)-1β to its active form. It has broad substrate specificity and is an apoptosis regulator. Caspase-1 is indirectly implicated in the pathology of cryopyrin-associated periodic syndrome (CAPS). It is a multiple inflammasome-associated protein associated with multiple sclerosis (MS) lesions and is a prime target for inhibitor screening.

CASPASE-1 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


CASPASE-1 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 17)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Creative Enzymes
1-516-855-7709
info@creative-enzymes.com United States 8748 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22784 58
Shanghai Universal Biotech Co.,Ltd 13774214275
zhouzz@univ-bio.com China 24994 58
Shanghai Yaji Biological Technology Co., Ltd. 021-34661275 15301693058
yajikit@163.com China 9670 58
United States Biological --
sales@advtechind.com United States 6075 58

  • ICE
  • ICE 1B HUMAN
  • IL-1BETA CONVERTING ENZYME
  • INTERLEUKIN-1BETA CONVERTING ENZYME
  • INTERLEUKIN-1B-CONVERTING ENZYME HUMAN
  • CASPASE-1 PROTEIN, RECOMBINANT HUMAN ACTIVE
  • CASPASE 1 HUMAN
  • CASPASE-1 HUMAN, RECOMBINANT, ACTIVE
  • CASPASE-1, HUMAN, RECOMBINANT, E COLI
  • CASPASE-1
  • ICE, Interleukin-1β-Converting Enzyme
  • Interleukin-1β-Converting Enzyme
  • Anti-CASP1, C-Terminal antibody produced in rabbit
  • Anti-CASP-1 (Cleaved-Asp210) antibody produced in rabbit
  • Anti-CASP1 (p20, Cleaved-Asn120) antibody produced in rabbit
  • CASP-1
  • IL-1 β converting enzyme
  • IL-1BC
  • P45) USP/EP/BP
  • 122191-40-6
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