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N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Struktur
127408-30-4
CAS-Nr.
127408-30-4
Englisch Name:
N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE
Synonyma:
Y-27152;Y 27152,Y27152;N-(Benzyloxy)-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)acetamide;N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE;N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE;Acetamide, N-[(3S,4R)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)-
CBNumber:
CB1837188
Summenformel:
C21H22N2O4
Molgewicht:
366.41
MOL-Datei:
127408-30-4.mol

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Eigenschaften

Siedepunkt:
513.4±60.0 °C(Predicted)
Dichte
1.28±0.1 g/cm3(Predicted)
storage temp. 
Store at RT
L?slichkeit
Soluble to 5 mM in ethanol with gentle warming and to 25 mM in DMSO
Aggregatzustand
Powder
pka
13.18±0.60(Predicted)

Sicherheit

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Y-27152, is a prodrug of the Kir6 (KATP) channel opener. It has also shown to produce antihypertensive effects in vivo, with minimal tachycardia following oral administration in hypertensive animals.

Biologische Aktivit?t

Prodrug of the K ATP channel opener Y-26763 (N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-hydroxyacetamide ). Inactive in vitro ; fails to modify tension in contracted aortic rings at concentrations up to 1 mM. In vivo, produces long-lasting antihypertensive effects with minimal tachycardia following oral administration in hypertensive animals.

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 35)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Alchem Pharmtech,Inc. 		8485655694
sales@alchempharmtech.com United States 63687 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Finetech Industry Limited 		+86-27-87465837 +8618971612321
 info@finetechnology-ind.com China 9639 58
Nanjing Bicbiotechnology Co., Ltd 		+86-2552131256 +86-18251840740
 sales@bicbiotech.com China 5994 58
TargetMol Chemicals Inc. 		+8613564774135
 zijue.cai@tsbiochem.com United States 19884 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
 3bsc@sina.com China 15839 69
Finetech Industry Limited 027-87465837 19945049750
 sales@finetechnology-ind.com China 9648 58
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8447 60
Hubei Chuangliankangcheng Pharmaceutical Co., Ltd. 027-65388397 18164111589
 3321478047@qq.com China 1994 55
Fan De(Beijing) Biotechnology Co., Ltd. 15911056312
 liming@bio-fount.com China 9729 58
  • N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE
  • Y-27152
  • N-(Benzyloxy)-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)acetamide
  • Acetamide, N-[(3S,4R)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)-
  • N-[(3S,4R)-6-CYANO-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-2H-1-BENZOPYRAN-4-YL]-N-(PHENYLMETHOXY)ACETAMIDE
  • Y 27152,Y27152
  • 127408-30-4
  • Potassium channel
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