1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

R-S?tze Betriebsanweisung:

R20/21/22:Gesundheitssch?dlich beim Einatmen,Verschlucken und Berührung mit der Haut.
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.

Beschreibung

1-Deoxymannojirimycin is a specific inhibitor of class I α-1,2-mannosidase (IC₅₀ = 0.02 μM), a key enzyme for N-glycan processing in the endoplasmic reticulum and Golgi and for targeting misfolded proteins for translocation out of the endoplasmic reticulum and degradation by the proteasome. By inhibiting α-1,2-mannosidase activity, this compound generates N-linked oligosaccharides with high mannose content, preventing misfolded protein degradation. This compound has been used for studies on glycoprotein processing and as a model for the development of anticancer and antiviral therapies.

Chemische Eigenschaften

White Crystalline Solid

Verwenden

Deoxymannojirimycin has been shown to be a potent inhibitor of the mammalian Golgi alpha- mannosidase 1 activity, blocking the conversion of high-mannose oligosaccharides to complex-type oligosaccharides. However, it does not inhibit the biosynthesis of lipid- linked oligosaccharides.

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28172	58
BOC Sciences	+1-631-485-4226	inquiry@bocsci.com	United States	19553	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22784	58
Wuhan Fortuna Chemical Co., Ltd	+86-027-59207850	info@fortunachem.com	China	5975	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49734	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Wuhan Fortuna Chemical Co.,Ltd	+8618007136271	hk@fortunachem.com	China	5998	58
Watson Biotechnology Co.,Ltd	+86-18186686046 +86-18186686046	sales01@watsonbiotech.cn	China	5841	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131957	58

73465-43-7()Verwandte Suche:

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• 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL, HCL
• 1,5-DIDEOXY-1,5-IMINO-D-MANNITOL HYDROCHLORIDE
• 1-DEOXYMANNOJIRIMYCIN HCL
• (+)-1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE
• 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE
• (2R,3R,4R,5R)-2-(HYDROXYMETHYL)-3,4,5-PIPERIDINETRIOL HYDROCHLORIDE
• 1-DeoxymannojirimycineHCl
• 1-Deoxymannojirimycinehydrochloride
• 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, hydrochloride, (2R,3R,4R,5R)-
• 1-Deoxymannojirimycin hydrochloride min. 98%
• DMJ HCl, (2R,3R,4R,5R)-2-(Hydroxymethyl)-3,4,5-piperidinetriol hydrochloride
• Manno-1-deoxynojiriMycin Hydrochloride
• DMJ, HYDROCHLORIDE
• DEOXYMANNOJIRIMYCIN HCL
• DEOXYMANNOJIRIMYCIN, HYDROCHLORIDE
• DEOXYMANNONOJIRIMYCIN HCL
• 1-DEOXYMANNOJIRIMYCIN HYDROCHLORIDE USP/EP/BP
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