8-(4-CHLOROPHENYLTHIO)-ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
8-CPT-cAMP is an efficient activator of cGK and cAMP-PK, and inhibitor of PDE.
Allgemeine Beschreibung
Cell-permeable cAMP analog that activates both protein kinase A and protein kinase G. Directly activates Epac, a Rap1 guanine-nucleotide exchange factor. Also acts as a potent inhibitor of cGMP-specific phosphodiesterase (IC
50 = 900 nM). Inhibits cAMP-specific phosphodiesterase at much higher concentrations (IC
50 = 25 μM).
Biochem/physiol Actions
Cell permeable: yes
8-(4-CHLOROPHENYLTHIO)-ADENOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte