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Neuromedin C (trifluoroacetate salt)

Neuromedin C (trifluoroacetate salt) Struktur
CAS-Nr.
Englisch Name:
Neuromedin C (trifluoroacetate salt)
Synonyma:
Neuromedin C (trifluoroacetate salt)
CBNumber:
CB14666728
Summenformel:
C50H73N17O11S
Molgewicht:
1120.28692
MOL-Datei:
Mol file

Neuromedin C (trifluoroacetate salt) Eigenschaften

Sicherheit

Neuromedin C (trifluoroacetate salt) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Neuromedin C is a bombesin-like neuropeptide that stimulates uterine smooth muscle contraction and the release of gastrin , somatostatin, and amylase in rats. Neuromedin C is a truncated form of gastrin-releasing peptide (GRP; Item Nos. 24415 | 24455) corresponding to the GRP amino acids 18-27. It inhibits GRP and bombesin binding to rat pancreatic membranes (IC50s = 0.4 and 2.2 nM, respectively), which can be reduced by sodium chloride and guanylyl imidodiphosphate . Neuromedin C induces scratching and mast cell degranulation in mice when administered intradermally at doses ranging from 1 to 300 nmol/site, which is inhibited by the BB2 bombesin receptor agonist RC-3095 and reduced in mast cell-deficient mice. Neuromedin C (3.2 nmol/kg, i.p.) reduces rat glucose consumption by approximately 50% for up to one hour.

Neuromedin C (trifluoroacetate salt) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Neuromedin C (trifluoroacetate salt) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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TargetMol Chemicals Inc.
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