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L-Leucyl-L-Leucine methyl ester (hydrochloride)

L-Leucyl-L-Leucine methyl ester (hydrochloride) Struktur
6491-83-4
CAS-Nr.
6491-83-4
Englisch Name:
L-Leucyl-L-Leucine methyl ester (hydrochloride)
Synonyma:
Leu-Leu-ome hydrochloride;H-Leu-leu-OMe hydrochloride;L-Leucyl-L-Leucine methyl ester;L-Leucyl-L-Leucine methyl ester (hydrochloride);L-Leucine, L-leucyl-, methyl ester, monohydrochloride;L-Leucyl-L-Leucine methyl ester hydrochloride, 10 mM in DMSO;methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate hydrochloride;lymphocytes,leukocytes,monocytes,pathway,LLeucylLLeucine methyl ester hydrochloride,LLOMe,inhibit,polymorphonuclear,stress,Leu-Leu methyl ester,cytotoxic,Inhibitor,L Leucyl L Leucine methyl ester hydrochloride,Endogenous Metabolite,endolysosomal
CBNumber:
CB13152666
Summenformel:
C13H27ClN2O3
Molgewicht:
294.81808
MOL-Datei:
6491-83-4.mol

L-Leucyl-L-Leucine methyl ester (hydrochloride) Eigenschaften

Schmelzpunkt:
177-181°C
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
L?slichkeit
DMSO (Slightly), Water (Slightly)
Aggregatzustand
Solid
Farbe
White to Off-White
Stabilit?t:
Hygroscopic

Sicherheit

L-Leucyl-L-Leucine methyl ester (hydrochloride) Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells. Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells.

L-Leucyl-L-Leucine methyl ester (hydrochloride) Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

L-Leucyl-L-Leucine methyl ester (hydrochloride) Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 57)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
BOC Sciences 		+1-631-485-4226
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TargetMol Chemicals Inc. 		+17819995354
 marketing@targetmol.com United States 32283 58
GL Biochem (Shanghai) Ltd. 		+86-021-61263370 +86-18901917034
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GL Biochem(Binhai) Ltd. 		+86-021-61263370 +8615301650015
 wuqiuyan@glschina.com China 2975 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439
 sales@nextpeptide.com China 19908 58
TargetMol Chemicals Inc.
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Wuhan Topule Biopharmaceutical Co., Ltd 		+8618327326525
 masar@topule.com China 8467 58
LEAPCHEM CO., LTD. 		+86-852-30606658
market18@leapchem.com China 43340 58
Aladdin Scientific
tp@aladdinsci.com United States 57505 58
Shanghai Hanhong Scientific Co., Ltd. 		+undefined17612118332
 Lucky@hanhonggroup.com China 6035 58

6491-83-4()Verwandte Suche:

  • L-Leucyl-L-Leucine methyl ester (hydrochloride)
  • methyl (2S)-2-[(2S)-2-amino-4-methylpentanamido]-4-methylpentanoate hydrochloride
  • Leu-Leu-ome hydrochloride
  • H-Leu-leu-OMe hydrochloride
  • L-Leucine, L-leucyl-, methyl ester, monohydrochloride
  • L-Leucyl-L-Leucine methyl ester
  • lymphocytes,leukocytes,monocytes,pathway,LLeucylLLeucine methyl ester hydrochloride,LLOMe,inhibit,polymorphonuclear,stress,Leu-Leu methyl ester,cytotoxic,Inhibitor,L Leucyl L Leucine methyl ester hydrochloride,Endogenous Metabolite,endolysosomal
  • L-Leucyl-L-Leucine methyl ester hydrochloride, 10 mM in DMSO
  • 6491-83-4
  • C13H26N2O3ClH
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