FAUC-365 Chemische Eigenschaften,Einsatz,Produktion Methoden
Beschreibung
FAUC-365 is a dopamine D
3 receptor antagonist (K
i = 0.5 nM). It is selective for dopamine D
3 receptors over dopamine D
1, D
2L, D
2S, and D
4 receptors (K
is = 8.8, 3.6, 2.6, and 0.34 μM, respectively) as well as the serotonin (5-HT) receptor subtypes 5-HT
1A and 5-HT
2 (K
is = 0.36 and 2 μM, respectively). FAUC-365 (1-10 mg/kg) prevents memory impairment in the novel object recognition test in dopamine transporter knockdown (DAT-KD) mice when administered prior to object learning.
FAUC-365 Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte