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AG 825

AG 825 Struktur
149092-50-2
CAS-Nr.
149092-50-2
Englisch Name:
AG 825
Synonyma:
AG 825;Zinc02572484;TYRPHOSTIN C15;AG 825 USP/EP/BP;TYRPHOSTIN AG 825;AG 825, ErbB2 inhibitor;AG 825 (Tyrphostin AG 825);AG 825 - CAS 149092-50-2 - Calbiochem;4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE;5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE
CBNumber:
CB1283828
Summenformel:
C19H15N3O3S2
Molgewicht:
397.47
MOL-Datei:
149092-50-2.mol

AG 825 Eigenschaften

storage temp. 
−20°C
L?slichkeit
DMSO: soluble
Aggregatzustand
Yellow solid
Farbe
Light yellow to yellow
Sensitive 
Light Sensitive

Sicherheit

S-S?tze: 22-24/25
WGK Germany  3

AG 825 Chemische Eigenschaften,Einsatz,Produktion Methoden

S-S?tze Betriebsanweisung:

S22:Staub nicht einatmen.
S24/25:Berührung mit den Augen und der Haut vermeiden.

Verwenden

A selective ErbB2 inhibitor

Definition

ChEBI: An organic sulfide that consists of 1,3-benzothiazole-2-thiol in which the hydrogen attached to the sulfur atom is replaced by a 5-[(1E)-3-amino-2-cyano-3-oxoprop-1-en-1-yl]-2-hydroxy-3-methoxybenzyl group. It acts as an epidermal growth factor receptor antagonist.

Biologische Aktivit?t

Selective ErbB2 inhibitor (IC 50 values are 0.15 and 19 mM at ErbB2 and ErbB1 respectively). Preferentially triggers p38 MAP kinase-dependent apoptosis in androgen-independent prostate cancer cells.

AG 825 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


AG 825 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 96)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Hubei Jusheng Technology Co.,Ltd.
18871490254
linda@hubeijusheng.com CHINA 28172 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427
sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32161 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250
1026@dideu.com China 22787 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38631 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15839 69
Suzhou Chireach Biomedical Technology Co., Ltd. 0512-65856968
sales@chireach.com China 59 70
VDM Biochemicals 0330-2528181
sales@vdmbio.com United States 510 64
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277
marketing_china@spectrumchemical.com China 9658 60

  • TYRPHOSTIN AG 825
  • TYRPHOSTIN C15
  • AG 825
  • 5-[(BENZTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYLIDENECYANOACETAMIDE
  • 5-[(BENZOTHIAZOL-2-YL)THIOMETHYL]-4-HYDROXY-3-METHOXYBENZYL-IDENECYANOACETAMIDE
  • 4-HYDROXY-3-METHOXY-5-(BENZOTHIAZOLYLTHIOMETHYL)BENZYLIDENECYANOACETAMIDE
  • 3-[3-[(2-Benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano- 2-Propenamide
  • Tyrphostin C15, 5-[(Benzothiazol-2-yl)thiomethyl]-4-hydroxy-3-methoxybenzylidenecyanoacetamide
  • AG 825 (Tyrphostin AG 825)
  • (E)-3-[3-[(2-BENZOTHIAZOLYTHIO)METHYL]-4-HYDROXY-5-METHOXYPHENYL]-2-CYANO-2-PROPENAMIDE
  • Zinc02572484
  • AG 825 USP/EP/BP
  • 2-Propenamide, 3-[3-[(2-benzothiazolylthio)methyl]-4-hydroxy-5-methoxyphenyl]-2-cyano-
  • AG 825 - CAS 149092-50-2 - Calbiochem
  • 3-(3-((Benzo[d]thiazol-2-ylthio)methyl)-4-hydroxy-5-methoxyphenyl)-2-cyanoacrylamide
  • AG 825, ErbB2 inhibitor
  • 149092-50-2
  • Cell Signaling and Neuroscience
  • Cell Biology
  • BioChemical
  • Kinase/Phosphatase Biology
  • Receptor Tyrosine Kinase Inhibitors
  • Epidermal Growth Factor Receptor (EGFR)
  • Protein Kinase
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