NSC 150117 hydrochloride Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(E/Z)-BCI hydrochloride has been used:

• to evaluate the role of the Duox-H₂O₂-Dusp6 derepression signaling pathway in heart regeneration
• as an MKP-1 inhibitor to investigate the role of MKP-1 on bexarotent-induced effects
• as a dual specificity phosphatase 6 (DUSP6) inhibitor to study its effects on the proliferation of SKOV3 cells

Biochem/physiol Actions

BCI is an allosteric inhibitor of Dusp6 that acts within the phosphatase domain to prevent the catalytic stimulation of phosphatase activity induced by ERK2 substrate binding. BCI also hyperactivates FGF signaling, since Dusp6 functions as a feedback regulator of FGF signaling.

NSC 150117 hydrochloride Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

NSC 150117 hydrochloride Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9806	58
Shanghai Han-Xiang Chemical Co., Ltd.	15971444841	amber@biochempartner.com	China	3061	58
Changzhou Chenhong Biotechnology Co., Ltd.	0519-85788828 13775037613	sales@chemrenpharm.com	China	3600	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11218	58
Shanghai hongqu biomedical technology co. LTD	88888888888	hongquchem@qq.com	China	5132	58
Jinan Jiuli Biotechnology Co. , Ltd.	15865264761	486064515@qq.com	China	4315	58

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• (E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one
• (E/Z)-BCI hydrochloride
• 2-benzylidene-3-(cyclohexylamino)-1-Indanone hydrochloride
• 3-(cyclohexylamino)-2,3-dihydro-2-(phenylmethylene)-1Hinden-1-one
• NSC 150117 hydrochloride
• BCI (hydrochloride)
• (E/Z)-BCI
• BCI hydrochloride - NSC 150117 hydrochloride
• (2Z)-2-benzylidene-3-(cyclohexylamino)-3H-inden-1-one
• (E)-BCI hydrochloride
• 95130-23-7