(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
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- CAS-Nr.
- 475473-26-8
- Englisch Name:
- (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
- Synonyma:
- CORM-3;Carbon monoxide releasing molecule 3;Tricarbonylchloro(glycinato)ruthenium;Tricarbonylchloro(glycinato)ruthenium (II);(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium;(OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium;Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-;inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)
- CBNumber:
- CB12717709
- Summenformel:
- C5H3ClNO5Ru
- Molgewicht:
- 293.6
- MOL-Datei:
- 475473-26-8.mol
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(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Eigenschaften
- storage temp.
- -20°C
- L?slichkeit
- H2O: soluble20mg/mL, clear
- Aggregatzustand
- powder
- Farbe
- light yellow to dark yellow
- Wasserl?slichkeit
- Soluble to 100 mM in water
Sicherheit
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
CORM-3 (carbon monoxide (CO) releasing molecule-3) has been used to study its effect on NLRP3 (leucine-rich-repeat-containing receptor, pyrin-domain-containing 3) inflammasome activation via glycolysis in macrophages and also on hyperglycemia-induced IL-1β (interleukin-1 β) production. It has also been used to study its protective function against H
2O
2-induced apoptosis using primary rabbit lens epithelial cells.
Biochem/physiol Actions
CORM-3 is a water-soluble carbon monoxide (CO) releasing molecule that can be used to study the effects of CO on cellular systems. Carbon monoxide (CO), produced during the degradation of heme by the enzyme heme oxygenase, has recently been found to be an important gaseous signaling mediator in mammalian cells CORM-3 has been shown to have anti-inflammatory and cardioprotective activity.
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(OC-6-44)-Tricarbonylchloro(glycinato)ruthenium Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 71)Lieferanten
- (OC-6-44)-Tricarbonylchloro(glycinato)ruthenium
- CORM-3
- Ruthenium, tricarbonylchloro(glycinato-κN,κO)-, (OC-6-44)-
- Carbon monoxide releasing molecule 3
- Tricarbonylchloro(glycinato)ruthenium (II)
- Tricarbonylchloro(glycinato)ruthenium
- inhibit,Inhibitor,Nuclear factor-kappaB,Nuclear factor-κB,CORM 3,CORM-3,NF-κB,NOD-like Receptor (NLR)
- (OC-6-44)-Tricarbonylchloro(glycinato-κN,κO)ruthenium
- 475473-26-8
- C5H4ClNO5Ru
- Inhibitors