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FL118

FL118 Struktur
151636-76-9
CAS-Nr.
151636-76-9
Englisch Name:
FL118
Synonyma:
FL118;CS-1718;10,11-(methylenedioxy)-(20R)-camptothecin;(R)-7-Ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione;10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7R)-;(5R)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.0?,?.01?,23.01?,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione
CBNumber:
CB12716227
Summenformel:
C21H16N2O6
Molgewicht:
392.36
MOL-Datei:
151636-76-9.mol

FL118 Eigenschaften

Siedepunkt:
812.1±65.0 °C(Predicted)
Dichte
1?+-.0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO : 2.7 mg/mL (6.88 mM; ultrasonic and warming and heat to 60°C)
Aggregatzustand
Solid
pka
11.18±0.20(Predicted)
Farbe
Off-white to yellow

Sicherheit

FL118 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(R)-FL-118 is a derivative of Camptothecin (C175150), which is antitumor alkaloid that binds to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I, trapping the enzyme in a covalent linkage with DNA.

FL118 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

FL118 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 26)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 32161 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471
 sales@sarms4muscle.com China 10473 58
Aladdin Scientific 		+1-+1(833)-552-7181
sales@aladdinsci.com United States 52924 58
Wuhan Jingkang en Biomedical Technology Co., Ltd 		+8613720134139
 orders@jknbiochem.com China 5221 58
Amadis Chemical Company Limited 		571-89925085
sales@amadischem.com China 131957 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057
 3003855609@qq.com China 7887 56
HangZhou YuHao Chemical Technology Co., Ltd. 0571-82693216
info@yuhaochemical.com China 2028 58
SPIRO PHARMA
eric_feng1954@126.com China 9248 55
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9806 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994
 2853530910@QQ.com China 8010 62
  • FL118
  • CS-1718
  • 10,11-(methylenedioxy)-(20R)-camptothecin
  • 10H-1,3-Dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(7H,13H)-dione, 7-ethyl-7-hydroxy-, (7R)-
  • (R)-7-Ethyl-7-hydroxy-7H-[1,3]dioxolo[4,5-g]pyrano[3',4':6,7]indolizino[1,2-b]quinoline-8,11(10H,13H)-dione
  • (5R)-5-ethyl-5-hydroxy-7,18,20-trioxa-11,24-diazahexacyclo[11.11.0.02,11.0?,?.01?,23.01?,21]tetracosa-1(13),2,4(9),14,16,21,23-heptaene-6,10-dione
  • 151636-76-9
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