6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
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- CAS-Nr.
- 1262888-28-7
- Englisch Name:
- 6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
- Synonyma:
- C43;CS-1649;Spautin-1;SPAUTIN-1;SPAUTIN1;Spautin 1 - MBCQ derivative C43;4-((4-Fluorobenzyl)amino)-6-fluoroquinazoline;6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine;6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine;6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine 98+%;6-Fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine
- CBNumber:
- CB12658835
- Summenformel:
- C15H11F2N3
- Molgewicht:
- 271.26
- MOL-Datei:
- 1262888-28-7.mol
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6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine Eigenschaften
- Schmelzpunkt:
- 211 °C
- Siedepunkt:
- 419.6±40.0 °C(Predicted)
- Dichte
- 1.366±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- L?slichkeit
- DMSO: soluble15mg/mL (clear solution)
- pka
- 5.75±0.50(Predicted)
- Aggregatzustand
- powder
- Farbe
- white to beige
- Stabilit?t:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine Chemische Eigenschaften,Einsatz,Produktion Methoden
Verwenden
Spautin-1 is a potent pharmacological autophagy inhibitor that promotes UVB-induced tumorigenesis. It is also a small-molecule drug that modulate autophagic pathways in different types of cancer.
Biochem/physiol Actions
Spautin-1 inhibits the activity of two ubiquitin-specific peptidases, USP10 and USP13, causing an increase in proteasomal degradation of class III PI3 kinase complexes, which have been shown to regulate autophagy.
6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 104)Lieferanten
1262888-28-7()Verwandte Suche:
- 6-fluoro-N-(4-fluorobenzyl)quinazolin-4-aMine
- 6-Fluoro-N-[(4-fluorophenyl)methyl]-4-quinazolinamine
- C43
- 4-((4-Fluorobenzyl)amino)-6-fluoroquinazoline
- Spautin-1
- 6-Fluoro-N-(4-fluorobenzyl)-4-quinazolinamine
- 6-Fluoro-N-[(4-fluorophenyl)methyl]quinazolin-4-amine
- Spautin 1 - MBCQ derivative C43
- CS-1649
- SPAUTIN-1;SPAUTIN1
- 6-Fluoro-N-(4-fluorobenzyl)quinazolin-4-amine 98+%
- 4-Quinazolinamine, 6-fluoro-N-[(4-fluorophenyl)methyl]-
- 1262888-28-7
- Inhibitors